Anomalous enhancement of fluorescence of carbon dots through lanthanum doping and potential application in intracellular imaging of ferric ion  

作　　者：Shenghong Yang Xiaohan Sun Zhaoyan Wang Xiayan Wang Guangsheng Guo Qiaosheng Pu 

机构地区：[1]State Key Laboratory of Applied Organic Chemistry, Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province, Department of Chemistry, Lanzhou University, Lanzhou 730000, China [2]School ofpharmacy, Lanzhou University, Lanzhou 730000, China [3]Beijing Key Laboratory for Green Catalysis and Separation, Department of Chemistry and Chemical Engineering, Beijing University of Technology, Beijing I00124, China

出　　处：《Nano Research》2018年第3期1369-1378,共10页纳米研究（英文版）

基　　金：The authors gratefully acknowledge the financial support from the National Natural Science Foundation of China （Nos. 21375005, 21575054 and 21527808）.

摘　　要：An anomalous enhancement of fluorescence of carbon dots （CDs） was observed via lanthanum （La） doping. La-doped CDs （La-CDs） were prepared through microwave pyrolysis within 4 min. With La^3＋ doping, the emission band shifted from blue to green although LaB＋ is non-fluorescent. The quantum yield and fluorescence lifetime improved by about 20% and 35%, respectively. All experiment results indicate that La^3＋ doping is an effective way to tune fluorescence and improve the performance of CDs. Another unique attribute of La-CDs is high sensitivity to Fe^3＋. The La-CD-based fluorescence probe was established and used for sensitive and selective detection of Fe^3＋ with a limit of detection of 91 nmol/L. The proposed fluorescence probe also was successfully employed to visualize intracellular Fe^3＋ in live HeLa cells through cell imaging. It was also shown that yttrium exhibited the same fluorescence enhancement effect as La. The results may provide a new route for preparing CDs with special properties.An anomalous enhancement of fluorescence of carbon dots （CDs） was observed via lanthanum （La） doping. La-doped CDs （La-CDs） were prepared through microwave pyrolysis within 4 min. With La^3＋ doping, the emission band shifted from blue to green although LaB＋ is non-fluorescent. The quantum yield and fluorescence lifetime improved by about 20% and 35%, respectively. All experiment results indicate that La^3＋ doping is an effective way to tune fluorescence and improve the performance of CDs. Another unique attribute of La-CDs is high sensitivity to Fe^3＋. The La-CD-based fluorescence probe was established and used for sensitive and selective detection of Fe^3＋ with a limit of detection of 91 nmol/L. The proposed fluorescence probe also was successfully employed to visualize intracellular Fe^3＋ in live HeLa cells through cell imaging. It was also shown that yttrium exhibited the same fluorescence enhancement effect as La. The results may provide a new route for preparing CDs with special properties.

关 键 词：rear earth doping carbon dots fluorescence tuning ferric ion cell imaging 

分 类 号：O562.5[理学—原子与分子物理] TM923.321[理学—物理]