膀胱癌图像引导放疗中基于软组织灰度值与基于内植标记物的锥形束CT校准比较  

Comparison of cone beam computed tomography calibrations based on soft tissue grey value and implanted markers in image-guided radiotherapy for bladder cancer

作　　者：田龙[1] 席强[1] 赵鑫[1] 刘月霞[2] 张遵浩 

机构地区：[1]河北北方学院附属第一医院,河北张家口075000 [2]张家口教育学院,河北张家口075000 [3]河北医科大学第一医院,河北石家庄050000

出　　处：《中国医学物理学杂志》2018年第1期31-35,共5页Chinese Journal of Medical Physics

摘　　要：目的:锥形束CT的X线容积成像系统(XVI)可执行多种方式校准。本研究目的是评价基于软组织灰度值与同基于膀胱内植标记物的校准方法准确性之间的差异。方法:所有病人接受锥形束CT图像引导下的常规图像引导放疗。将病人分为基于软组织灰度值自动校准试验组和基于膀胱内植标记物手动校准参考组,在确认标记物准确性后,比较了两种方法在3D空间向量和左右(LR)、头脚(SI)、前后(AP)3个方向上的差异。结果:两种方法的3D空间向量差异平均值为0.65 cm;左右方向(LR),头脚方向(SI),前后方向(AP)差异平均值分别为0.03、0.45和1.67 cm。结论:膀胱癌图像引导放疗中基于软组织灰度值的自动校准方法在准确度上劣于基于膀胱内植标记物的手动校准。避免标记物植入和新的图像计算、分析方法是未来发展趋势。Objective The X-ray volume imaging system of cone beam computed tomography can perform various ways of calibration.This study aims to evaluate and compare the accuracy of calibrations based on soft tissue grey value and bladder implanted markers.Methods All the patients receiving radiotherapy guided by cone beam computed tomography images were divided into two groups,namely experimental group（automatic calibration based on soft tissue grey value） and reference group（manual calibration based on bladder implanted markers）.After the accuracy of implanted markers was confirmed,we compared the differences between two calibration methods in three-dimensional spatial vectors and left-right,superior-inferior,anteriorposterior directions.Results The mean differences between two calibration methods in three-dimensional spatial vectors and left-right,superior-inferior,anterior-posterior directions were 0.65,0.03,0.45 and 1.67 cm,respectively.Conclusion In the imageguided radiotherapy for bladder cancer,the accuracy of automatic calibration based on soft tissue grey value is lower than that of the manual calibration based on bladder implanted markers.Avoiding implanted markers,new image calculations and analysis methods are the future development trends.

关 键 词：膀胱癌 锥形束CT 图像引导放疗 软组织灰度值 内植标记物 

分 类 号：R812[医药卫生—放射医学]