肝硬化患者血清C反应蛋白检测的临床价值  

Clinical value of serum C reactive protein in patients with liver cirrhosis

作　　者：权政 崔春吉 

机构地区：[1]延边大学附属医院消化内科,133000

出　　处：《中国社区医师》2018年第8期124-124,126,共2页Chinese Community Doctors

摘　　要：目的:探讨血清C反应蛋白的检测在肝硬化中的临床价值。方法:检测对照组142例与978例肝硬化患者的血清CRP,分析血清CRP变化与肝硬化患者的预后、肝功能损害程度以及某些并发症等的关系。结果:肝硬化患者血清CRP显著高于对照组(P<0.01);肝硬化死亡组血清CRP显著高于存活组(P<0.01);肝硬化肝功能B级组血清CRP显著高于肝功能A级组(P<0.01),肝功能C级组血清CRP显著高于肝功能A级组(P<0.01)与B级组(P<0.01);肝硬化并发肝性脑病组血清CRP显著高于未并发肝性脑病组(P<0.01);肝硬化并发上消化道出血组血清CRP显著高于未并发上消化道出血组(P<0.05)。结论:肝硬化患者血清CRP明显升高,并与肝硬化患者的预后、肝功能损害程度及是否并发肝性脑病、上消化道出血等因素有密切关系。Objective：To investigate the clinical value of the detection of serum C reactive protein in liver cirrhosis.Methods：142 cases in the control group and 978 cases in the of cirrhosis were detected Serum CRP levels.The relationship between serum CRP level and prognosis,liver function damage and some complications were analyzed.Results：The serum CRP was significantly higher than the control group（P〈0.01）;liver cirrhosis serum CRP was significantly higher than the survival group（P〈0.01）;liver function in B group serum CRP was significantly higher than that in the liver function A group（P〈0.01）;serum CRP in the liver function C group was significantly higher than that in the liver function A group（P〈0.01） and the B group（P〈0.01）;liver cirrhosis complicated with hepatic encephalopathy group serum CRP was significantly higher than that of non hepatic encephalopathy group（P〈0.01）;the serum CRP was significantly higher than that of tract hemorrhage complicated with upper digestive tract hemorrhage group without liver cirrhosis complicated with upper digestive（P〈0.05）.Conclusion：The serum level of CRP is significantly increased in cirrhosis patients,and it is closely related to the prognosis,liver function damage,hepatic encephalopathy and upper gastrointestinal bleeding.

关 键 词：血清CRP 肝硬化 预后 肝功能损害程度 并发症 

分 类 号：R446.1[医药卫生—诊断学] R575.2[医药卫生—临床医学]