浙江中北部农村居民慢性肾脏病患病率危险因素研究  

A cross-sectional study on prevalence of chronic kidney disease and related risk factors among rural residents of north-central areas of Zhejiang

作　　者：金炜 嵇水玉[2] 姚炯[2] 徐梦秋[2] 钱莎莎 陈晓颖 陈勇[4] 暨利军 许秀君[2] 陈惠仙[2] 潘敏燕 周连芬 孙贤 杨渊 沈泉泉[2] 林波[2] 赵湘[2] 

机构地区：[1]桐乡市第一人民医院肾内科,浙江桐乡314500 [2]浙江省人民医院(杭州医学院附属人民医院)肾脏病科 [3]浙江大学附属第一医院肾脏病中心 [4]浙江省磐安县人民医院 [5]浙江省仙居县人民医院 [6]海宁市中心医院

出　　处：《中国预防医学杂志》2018年第2期91-96,共6页Chinese Preventive Medicine

基　　金：浙江省医药卫生平台计划(重点资助)(2015ZDA005)

摘　　要：目的探讨浙江中北部农村居民慢性肾脏病(chronic kidney disease,CKD)患病率及相关危险因素。方法对浙江中北部磐安县高二乡、海宁市永福村、海宁市许桥村、桐乡市路家园村,4个村落、118个村民小组内居住5年以上≥18岁原住居民1 654人,通过CKD相关危险因素的问卷调查、体格检查及实验室检查,进行横断面研究。根据浙江省第六次人口普查数据中乡村地区人口年龄、性别分布计算CKD标化患病率,分析CKD相关危险因素。结果经人口年龄性别标化后,该人群CKD总患病率为9.44%(95%CI8.03~10.85),白蛋白尿患病率8.02%(95%CI6.71~9.33),肾功能下降患病率2.65%(95%CI1.88~3.42)。CKD知晓率为6.49%。性别、年龄、BMI、收缩压、空腹血糖、血尿酸是CKD的独立危险因素,舒张压、胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、甘油三酯与CKD发病无关。结论浙江中北部农村居民CKD患病率随年龄、BMI、收缩压、空腹血糖、血尿酸增加有增长趋势,且女性患病率高于男性。Objective To understand the prevalence of chronic kidney disease（CKD）among rural residents of north central areas of Zhejiang,and to analyze the related risk factors. Methods A total of 1 654 native residents aged ≥18 years and living at least 5 years in the areas were selected from four villages in north-central areas of Zhejiang.All participants completed the questionnaire about the risk factors related to CKD and received physical examination as well as urine and blood test.The standardized prevalence of CKD was calculated based on the distribution of age and gender in the sixth census data in rural areas of Zhejiang.Risk factors related to CKD were analyzed by univariate analysis and multivariable logistic regression analysis. Results After adjusting the age and gender,the overall prevalence of CKD was 9.44%（95% CI：8.03-10.85）,the prevalence of albuminuria and reduced renal function were 8.02%（95%CI：6.71-9.33）and 2.65%（95%CI：1.88-3.42）.The awareness rate for CKD was 6.49%.Gender,age,BMI,SBP,FBG（fasting blood-glucose）,blood uric acid were found to be independent risk factors of CKD,while DBP,cholesterol,HDL-C,LDL-C and triglyceride were factors unrelated to CKD. Conclusions The prevalence of CKD of rural residents in north-central areas of Zhejiang shows a up-ward trend along with age and the increase of BMI,SBP,FBG and blood uric acid.The prevalence of female residents is significantly higher than male individuals.

关 键 词：慢性肾脏病 患病率 农村居民 流行病学调查 横断面研究 浙江中北部 

分 类 号：R692[医药卫生—泌尿科学]