鼻炎宁颗粒致过敏性休克  

Anaphylactic shock caused by Biyanning granule（鼻炎宁颗粒）

作　　者：郭虎[1] 黄道秋[1] 

机构地区：[1]重庆三峡中心医院药学部,404000

出　　处：《药物不良反应杂志》2018年第1期73-75,共3页Adverse Drug Reactions Journal

摘　　要：1例31岁女性患者因鼻炎口服自行购买的鼻炎宁颗粒15 g，用药后即刻出现心悸、气促，多汗、全身乏力，伴咽喉梗阻感、腹痛、恶心、呕吐，呕吐物为胃内容物，血压最低降至49/30 mmHg （1 mmHg = 0.133 kPa），约30 min后出现嗜睡。考虑为鼻炎宁颗粒所致过敏性休克，立即给予静脉滴注0.9%氯化钠注射液、静脉泵入盐酸多巴胺注射液、静脉注射地塞米松磷酸钠注射液及肌内注射注射用肾上腺素等抗过敏性休克治疗。约50 min后，患者血压升至80/57 mmHg；2 h后症状缓解，血压波动在90～100/60～80 mmHg；12 h后症状消失，血压 106/66 mmHg。A 31-year-old female patient with rhinitis received Biyanning granule 15 g by herself. The patient developed palpitation, dyspnea, idrosis, debilitation, feeling obstruction of throat, abdominal pain, nausea, vomiting （gastric content）, and decrease of blood pressure （49/30 mmHg）, shortly afterwards. She developed drowsiness about 30 minutes later. She was diagnosed as anaphylactic shock due to Biyanning granule. The patient received anti anaphylactic shock treatments which included an IV infusion of 0.9% sodium chloride injection, intravenous pumping of dopamine hydrochloride injection, intravenous injection of dexamethasone sodium phosphate injection, and intramuscular injection of epinephrine for injection. About 50 minutes later, her blood pressure increased to 80/57 mmHg. Two hours later, the above-metioned symptoms relieved, blood presure fluctuated between 90-100/60-80 mmHg. Twelve hours later, the symptoms disappeared, blood pressure was 106/66 mmHg.

关 键 词：过敏性反应 鼻炎宁颗粒 

分 类 号：R969[医药卫生—药理学]