卵巢低反应妇女助孕治疗后临床结局的影响因素分析  

An analysis of influencing factors on the outcome of women with poor ovarian responders

作　　者：夏弘 姚辰希 张静[1] 白晓红[1] 

机构地区：[1]天津医科大学总医院,300052

出　　处：《中国计划生育学杂志》2018年第3期211-214,共4页Chinese Journal of Family Planning

摘　　要：目的:探讨体外受精-胚胎移植(IVF-ET)/卵胞浆内单精子注射(ICSI)助孕治疗中卵巢低反应妇女临床结局的影响因素。方法:回顾性分析2012年1月—2016年9月在本院生殖中心行IVF/ICSI-ET助孕治疗,共122例卵巢低反应妇女取卵周期的临床及实验室资料,根据妇女的临床结局分为妊娠组(n=26)和非妊娠组(n=96);根据妇女年龄分为<35岁组(n=21)、35~40岁组(n=36)和>40岁组(n=65)。结果:妊娠组与非妊娠组的年龄和子宫内膜厚度均有差异(P<0.05);高龄妇女的种植率和临床妊娠率显著降低(P<0.05);logistic多因素回归分析显示年龄和子宫内膜厚度与临床结局有关。结论:年龄和子宫内膜厚度是影响卵巢低反应妇女IVF-ET/ICSI临床结局的重要因素。Objective： To explore influencing factors on the clinical outcome of women with poor ovarian responders during in vitro fertilization-embryo transfer （IVF-ET） or intracytoplasmic sperm injection （ICSI）. Methods： A retrospective analysis was conducted and the data was collected from 122 IVF-ET/ICSI cycle patients with poor ovarian response from the reproductive medicine center of the general hospital of Tianjin medical university between Jan. 2012 and Sep. 2016. All included patient were divided into pregnant group （n=26） and non-pregnant group （n=96）. And all the patients were also divided into group A （〈35 years old, n=21） , group B（35-40 years old, n=36）and group C （〉40 years old, n=65）according to their age. Results： There were significant different in age and endometrial thickness between the pregnant group and the non-pregnant group（P〈0,05）. The implantation rate and pregnancy rate of patients over 40 years old decreased significantly. Logistic regression analysis results showed that age and endometrial thickness had contributed to clinical outcome. Conclusion： Age and the endometrial thickness are the important influencing factors on the outcome of women with poor ovarian responders in IVF-ET/ICSI.

关 键 词：体外受精-胚胎移植 卵巢低反应 临床结局 子宫内膜厚度 

分 类 号：R714.8[医药卫生—妇产科学]