ENDOCOCHLEAR POTENTIAL AND POTASSIUM CONCENTRATION RECORDING IN MINIPIG COCHLEA  

作　　者：GUO Weiwei CHEN Lei LI Dengke SUN Wei YANG Shiming 

机构地区：[1]Department of Otolaryngology, Head & Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital [2]State Key Laboratory for Agro-biotechnology, China Agricultural University [3]Center for Hearing and Deafness,SUNY at Buffalo

出　　处：《Journal of Otology》2012年第2期102-104,共3页中华耳科学杂志（英文版）

摘　　要：Objective To record the endocochlear potential (EP) and calculate potassium concentration [K+] in Minipig cochleae. Methods We used multi-barreled electrodes to measure the EP and the potential, [K + ]. EP and potassium electrode recording were made in 9 cochleae from 5 minipigs to get normal EP values. Results The average EP value in the cochlea from the minipigs was 77.3 ± 14 mV. The average [K+] for the minipigs was 147.1 ± 13 mM. Conclusions The EP and potential, [K + ] in minipigs are lower than in the human and rodents. This may be the reason why porcine ABR thresholds are slightly higher than humans and rodents.Objective To record the endocochlear potential (EP) and calculate potassium concentration [K+] in Minipig cochleae. Methods We used multi-barreled electrodes to measure the EP and the potential, [K + ]. EP and potassium electrode recording were made in 9 cochleae from 5 minipigs to get normal EP values. Results The average EP value in the cochlea from the minipigs was 77.3 ± 14 mV. The average [K+] for the minipigs was 147.1 ± 13 mM. Conclusions The EP and potential, [K + ] in minipigs are lower than in the human and rodents. This may be the reason why porcine ABR thresholds are slightly higher than humans and rodents.

关 键 词：stria vascularis potassium secretion endocochlear potential MINIPIG 

分 类 号：R764[医药卫生—耳鼻咽喉科]