恶性实体瘤化疗患儿癌因性疲乏对抑郁的影响  

Impact of cancer-related fatigue on depression among children with malignant solid tumor during chemotherapy treatment

作　　者：郭凤丽 苏玲[2] 赵婧 强万敏[3] 

机构地区：[1]天津中医药大学研究生院,天津300193 [2]天津市肿瘤医院儿童肿瘤科 [3]天津市肿瘤医院护理部

出　　处：《护理学杂志》2018年第3期20-22,共3页Journal of Nursing Science

摘　　要：目的了解恶性实体瘤患儿化疗期间癌因性疲乏与抑郁情绪的现状,为针对性护理干预提供参考。方法采用中文版儿童多维度疲乏量表及儿童抑郁障碍自评量表对93例恶性实体瘤化疗患儿进行问卷调查。结果恶性实体瘤化疗患儿疲乏得分70.12±12.67,抑郁得分11.55±4.65;分层回归分析结果示年龄、住院次数、疲乏是抑郁的影响因素(P<0.05,P<0.01;R^2=0.360),其中疲乏影响最大(β'=-0.480)。结论恶性实体瘤患儿疲乏程度重,严重影响抑郁情绪。护理人员可通过控制患儿疲乏症状以减轻其抑郁情绪,从而提高患儿的生活质量。Objective To investigate the levels of cancer-related fatigue and depression in children with malignant solid tumor during chemotherapy treatment.Methods Totally 93 children undergoing chemotherapy for malignant solid tumor were surveyed by using the Pediatric Quality of Life Inventory Multidimensional Fatigue Scale（PedsQLTM MFS）and Depression Self-rating Scale for Children（DSRSC）.Results The sample scored 70.12±12.67 on fatigue and 11.55±4.65 on depression.Hierarchical logistic regression analysis indicated that age,the number of hospitalizations and fatigue were predictors of depression（P〈0.05,P〈0.01;R2=0.360）,and fatigue was predominant factor（β＇=-0.480）.Conclusion Children with malignant solid tumor had severe fatigue,which might cause depressive symptoms.Nurses could alleviate depression in children by controlling their fatigue,thus to promote quality of life.

关 键 词：儿童 恶性实体瘤 化疗 癌因性疲乏 抑郁 

分 类 号：R473.72[医药卫生—护理学] R395.2[医药卫生—临床医学]