PM2.5与变应性鼻炎患者生活质量相关性研究  

The correlation study between PM2.5 and the life quality in patients with allergic rhinitis

作　　者：罗嘉莹[1] 胡佳晴 陈钊[1] 郭梓君 孙宝清[1] LUO Jiaying, HU Jiaqing ,CHEN Zhao, GUO Zijun, SUN Baoqing(State Key Laboratory of Respiratory Disease, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510182, Chin)

机构地区：[1]广州医科大学附属第一医院广州呼吸疾病研究所呼吸疾病国家重点实验室变态反应科,广州510182

出　　处：《临床耳鼻咽喉头颈外科杂志》2018年第4期295-297,共3页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

基　　金：广州市医药卫生科技项目(No:20161A011066)

摘　　要：目的:探讨变应性鼻炎(AR)患者生活质量与其周边环境的PM2.5浓度的关系。方法:选取临床上确诊的AR患者52例,让患者连续填写鼻结膜炎相关生活质量问卷(RQLQ),并连续测试患者生活环境的PM2.5浓度1个月(31d),采用SPSS 19.0统计软件进行数据的录入和分析,对结果进行描述性统计分析、Spearman相关分析以及非参数秩和检验,以P<0.05为差异有统计学意义。结果:在RQLQ量表的各个症状评分中,鼻部症状(r=0.121,P<0.01)、日常活动(r=0.146,P<0.01)、实际问题(r=0.099,P<0.01)与PM2.5浓度有统计学意义;而睡眠问题(r=0.059,P=0.051)、非鼻眼症状(r=0.042,P=0.169)、情感问题(r=0.042,P=0.168)、眼部症状(r=0.087,P=0.274)与PM2.5的变化无统计学意义。男女患者在日常活动、非鼻眼症状及情感问题3个项目上的评分存在显著差异。女性AR患者在日常活动、非鼻眼症状、实际问题、鼻部症状和情感问题等方面与PM2.5变化显著相关;而男性AR患者仅日常活动和鼻部症状与PM2.5变化显著相关。结论:PM2.5的浓度变化影响AR患者的生活质量,PM2.5浓度越大,AR患者的生活质量越低。Objective：This study aims to research the relationship betweeen allergic rhinitis（AR）patients life quality and the PM2.5 concentration.Method：Fifty-two patients with clinically diagnosed AR were enrolled in this study.Patients were asked to fill in the questionnaire about the quality of life of rhinoconjunctivitis（RQLQ）continuously.The concentrations of PM2.5 in their living environment were continuously tested for one month（31 days）and SPSS 19.0 software was used to analyze data through descriptive statistical method,Spearman correlation analysis and nonparametric test.P〈0.05 was considered statistically significant.Result：There were significant association between PM2.5 and nasal symptoms（r=0.121,P〈0.01）,daily activities（r=0.146,P〈0.01）and practical problems（r=0.099,P〈0.01）.However,sleep（r=0.059,P=0.051）,non-hay fever symptoms（r=0.042,P=0.169）,emotion（r=0.042,P=0.168）,eye symptoms（r=0.087,P=0.274）and PM2.5 had no statistical significance.AR patients have faced notable differences in genders.The scores of activities,non hay fever symptoms and emotions also showed the difference.Female AR patients have demonstrated the statistical significance with the concentration of PM2.5 among the activity,non hay fever symptoms,practical problems,nasal symptoms and emotions.While the male AR patients existed a statistical significance in the concentration of PM2.5 only between the activity and nasal symptoms.Conclusion：PM2.5 concentration is negatively associated with the life quality of AR patients.The higher concentration of PM2.5,the lower AR patients quality of life they got.

关 键 词：鼻炎 变应性 细颗粒物 鼻结膜炎相关生活质量问卷 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]