普米克令舒氧驱雾化吸入联合阿斯美及顺尔宁治疗咳嗽变异性哮喘疗效观察  

Observation of efficacy of pulmicort oxygen-driven inhalation combined with Asmeton and Singulair in the treatment of cough variant asthma

作　　者：何孝柱 HE Xiao-zhu(Department of Respiratory Medicine, Jiangsu Kunshan Dianshan Lake People.s Hospital, Kunshan 215345, Chin)

机构地区：[1]江苏省昆山市淀山湖人民医院呼吸内科,215345

出　　处：《中国实用医药》2018年第8期88-90,共3页China Practical Medicine

摘　　要：目的观察吸入用布地奈德混悬液(普米克令舒)氧驱雾化吸入联合复方甲氧那明胶囊(阿斯美)及孟鲁司特钠片(顺尔宁)治疗咳嗽变异性哮喘(CVA)的临床疗效。方法 64例咳嗽变异性哮喘患者,随机分为观察组与对照组,各32例。对照组给予班布特罗和氯雷他定治疗,观察组给予普米克令舒、阿斯美及顺尔宁联合治疗。观察两组临床效果。结果观察组总有效率为93.75%,高于对照组的71.88%,差异有统计学意义(P<0.05)。治疗后观察组第一秒用力呼气容积占预计值百分比(FEV1%)、用力肺活量占预计值百分比(FVC%)、呼气高峰流量(PEFR)均优于治疗前,差异有统计学意义(P<0.05),且治疗后观察组均优于对照组,差异有统计学意义(P<0.05)。结论普米克令舒氧驱雾化吸入联合阿斯美及顺尔宁治疗咳嗽变异性哮喘疗效明显,值得临床推广。Objective To observe the clinical efficacy of budesonide suspension for inhalation（Pulmicort） oxygen-driven inhalation combined with compound methoxyphenamine capsules（Asmeton） and montelukast sodium tablets（Singulair） in the treatment of cough variant asthma（CVA）. Methods A total of 64 cough variant asthma patients were randomly divided into observation group and control group, with 32 cases in each group. The control group was treated with bambuterol and loratadine, and the observation group was treated with Pulmicort, Asmeton and Singulair. The clinical effect in two group was observed. Results The observation group had higher total effective rate as 93.75% than 71.88% in the control group, and the difference was statistically significant（P〈0.05）. After treatment, the observation group had better forced expiratory volume in 1 second percentage of expected value（FEV1%）, forced vital capacity percentage of expected value（FVC%）, peak expiratory flow rates（PEFR） than before treatment, and the difference was statistically significant（P〈0.05）. After treatment, the observation group was better than the control group, and the difference was statistically significant（P〈0.05）. Conclusion Combination of pulmicort oxygen-driven inhalation, Asmeton and Singulair shows obvious efficacy in the treatment of cough variant asthma, and it is worthy of clinical promotion.

关 键 词：咳嗽变异性哮喘 吸入用布地奈德混悬液 复方甲氧那明胶囊 孟鲁司特钠片 

分 类 号：R562.25[医药卫生—呼吸系统]