高频电针对心肌缺血损伤大鼠经穴及非穴皮肤温度的影响  

Influence of high frequency electroacupuncture on skin temperature around meridian acupoints,and non-menridian sham acupoints in rats with myocardial ischemia

作　　者：白红新[1] 嵇波[1] 赵国桢[1] 王丹[1] 严明娜 孙晓敏[1] 路雅雯 戴健[1] 刘翼天 葛云鹏 苏杭 吴娇娟 游敏[1] 程凯[1] 李志刚[1] Bai Hongxin, Ji Bo, Zhao Guozhen, Wang Dan, Yan Mingna, Sun Xiaomin, Lu Yawen, Dai Jian, Liu Yitian, Ge Yunpeng, Su Hang, Wu Jiaojuan, You Min, Chen Kai, Li Zhigang(School of Acupuncture-Moxibustion and Tuina, Beijing University of Chinese Medicine, Beijing 100029, Chin)

机构地区：[1]北京中医药大学针灸推拿学院,北京100029

出　　处：《北京中医药大学学报》2018年第2期148-153,共6页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(No.81373558;No.81674059)~~

摘　　要：目的借助大鼠心肌缺血损伤模型,探讨高频电针刺激"内关"穴或非穴后,相关经穴、非相关经穴及非区穴皮肤温度的变化规律及其随时间的变化情况。方法雄性Wistar大鼠随机分为空白对照组、假手术组、心肌缺血损伤组(简称模型组)、高频电针经穴组和高频电针非穴组。高频电针经穴组、高频电针非穴组均在成功制备模型的基础上给予电针治疗。于第3天电针治疗后30、60 min,应用红外热成像仪记录"内关"穴、"阳陵泉"穴、非穴区皮肤红外热像图并进行数据统计分析。结果与空白对照组比较,模型组"内关"穴区皮肤温度显著降低(P<0.01)。与模型组比较,高频电针经穴组"内关"穴区皮肤温度升高(P<0.01),高频电针非穴组"内关"穴、"阳陵泉"穴、非穴区皮肤温度差异无统计学意义;其中高频电针经穴组"内关"穴区皮肤温度以治疗后30 min更接近空白对照组。结论 "内关"穴区皮肤温度能相对特异性地反映大鼠心肌所处的不同状态,高频电针"内关"穴能阻抑由于心肌缺血损伤诱发的相关经穴皮肤温度的下降,其机制有待进一步研究。Objective To compare the skin temperature around relevant and irrelevant meridian acupoints,or non-meridian sham acupoints in rats with myocardial ischemia by high frequency electro-acupuncture（ EA） at Neiguan（ PC6） point or sham acupoint,in healthy rats and myocardial ischemic rats.Methods Fifty male Wister rats were randomly divided into five groups： blank control group,sham-operation group,model group,high frequency EA at Neiguan group（ PC6） and high frequency electro-acupuncture at sham acupoint groups. Rats in high frequency EA at and at sham acupoints group received EA intervention after their models were successfully established. Temperature around the skin of Neiguan（ PC6）,Yanglingquan（ GB34） and sham acupoints were measured and recorded by infrared thermogra-phy in every group at 30 minutes 60 minutes after three-day treatment for statistical analysis. Results Compared with the blank control group,skin temperature around PC6 in model groups was significantly lower（ P 0. 01）; Compared with the model group,skin temperature around PC6 in high frequency EA at PC6 group was significantly increased（ P 0. 01）; Skin temperature around PC6,GB34 and sham acupoint in high frequency EA at sham acupoint groups presented with no statistical significance; skin temperature around PC6 in high frequency EA at PC6 group was similar to the skin temperature of blank control group,which was measured 30 minutes after the treatment. Conclusion The relative specificity of skin temperature around PC6 can be useful for the reflection of different conditions of rats＇ myocardium. High-frequency electro-acupuncture at PC6 can prevent the reduction of skin temperature caused by myocardial ischemia injury,of which the mechanism needs further study.

关 键 词：高频电针 心肌缺血 皮肤温度 经穴 大鼠 

分 类 号：R285.5[医药卫生—中药学]