青海省囊谦县8～10岁儿童甲状腺容积影响因素分析  

Thyroid volume of children aged 8 - 10 years old in Nangqian County of Qinghai Province and influencing factors

作　　者：甘培春[1] 陈勋[1] 蔡生花[1] 李亚楠[1] 胡兰盛[1] 杨佩珍[1] 何多龙[1] 李勇[1] 余慧珍[1] 孟献亚[1] Gan Peichun, Chen Xun, Cai Shenghua, Li Ya＇nan, ttu Lansheng, Yang Peizhen, He Duolong, Li Yong, Yu Huizhen, Meng Xianya(Department for Endemic Disease Prevention and Control, Qinghai Institute .for Endemic Diseases Prevention and Control, Xining 811602, China （Gan PC, Chen X, Cai SH, Li YN, Hu LS, Yang PZ, He DL, Li Y, Yu HZ, Meng XY）)

机构地区：[1]青海省地方病预防控制所地方病预防控制科,西宁811602

出　　处：《中华地方病学杂志》2018年第3期218-220,共3页Chinese Journal of Endemiology

基　　金：国家自然科学基金（81160332）

摘　　要：目的分析甲状腺容积与尿碘水平、身高、体重各个指标之间的关系，为评价碘缺乏病病情提供科学依据。方法2014年抽取青海省囊谦县10个乡镇中心学校的8-10岁儿童，测量身高、体重，并采集即时尿样，用砷铈催化分光光度法检测尿碘；采用B超进行甲状腺容积检测。比较分析不同尿碘、身高、体重、年龄、性别儿童甲状腺容积之间的差异，以及甲状腺容积与身高、体重、性别、年龄间的相关关系。结果共检查8-10岁儿童773名，甲状腺容积呈偏态分布（W = 0.088，P 〈 0.05），甲状腺容积中位数为3.53 ml，四分位数（P25、P75）为3.05、4.15 ml。不同尿碘水平儿童甲状腺容积比较差异无统计学意义（H = 1.644，P 〉 0.05）；不同身高组儿童甲状腺容积比较差异有统计学意义（H = 59.845，P 〈 0.05），甲状腺容积与身高呈正相关关系（r = 0.389，P 〈 0.05）；不同体重儿童甲状腺容积比较差异有统计学意义（H = 64.888，P 〈 0.05），甲状腺容积与体重呈正相关（r = 0.359，P 〈 0.05）；不同年龄儿童甲状腺容积比较差异有统计学意义（H = 28.590，P 〈 0.05），且两者呈正相关（r = 0.155，P 〈 0.05）。结论甲状腺容积与儿童年龄、身高、体重因素有关，因此，采用B超法对儿童个体甲状腺容积的诊断，除考虑年龄因素外，还应考虑身高、体重因素对甲状腺容积的影响，降低甲状腺肿大的诊断误差。ObjectiveTo investigate the relationship between thyroid volume and multiple body indexes such as urinary iodine level, height, and weight, respectively, in order to provide a theoretical basis for evaluation of goiter disease in the future.MethodsThe height and weight were measured, and urine samples were collected from children aged 8 to 10 years old from 10 township schools of Nangqian County in Qinghai Province in 2014 and urinary iodine was tested via the As （Ⅲ）-Ce4＋ catalytic spectrophotometry method. Meanwhile, the thyroid volume was immediately measured via the B-ultrasound method. Statistical analyses were employed finally to assess the difference and correlation between thyroid volume and multiple physiological indexes including urinary iodine level, height, weight, gender and age.ResultsThe thyroid volume of 773 children aged 8 to 10 years old showed skewed distribution （W = 0.088, P 〈 0.05）, with median of 3.53 ml and quartile of 3.05, 4.15 ml. The thyroid volume was not significantly different between different urinary iodine levels （H = 1.644, P 〉 0.05）. There were significant differences of the thyroid volume among different height groups, weight groups and age groups （H = 59.845, 64.888, 28.590, P 〈 0.05）, and the thyroid volume was positively correlated with height weight and age, respectively （r = 0.389, 0.359, 0.155, P 〈 0.05）.ConclusionsThe thyroid volume is related to the level of children＇s physiological parameters, such as age, height, weight. Therefore, the diagnosis of thyroid volume via the B-ultrasound method for a individual child should not only take age, but also height and weight into account, to reduce the diagnostic error of goiter disease.

关 键 词：甲状腺 尿 碘 身高 体重 年龄 

分 类 号：R723.2[医药卫生—儿科]