气相色谱法测定工作场所空气中甲基异戊基甲酮  

Determination of methyl isoamyl ketone in workplace air by gas chromatography method

作　　者：李仓廪 宋利群 邹薇[2] 李龙 张志虎[2] 邵华[2] LI Cang- lin , SONG Li -qun, ZOU Wei, LI Long, ZHANG Zhi -hu, SHAO Hua(School of Medicine and Life Sciences, University of Ji＇nan, Ji＇nan, Shandong 250062, Chin)

机构地区：[1]济南大学医学与生命科学学院,山东济南250062 [2]山东省医学科学院山东省职业卫生与职业病防治研究院,山东济南250062

出　　处：《中国卫生检验杂志》2018年第4期412-414,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的研究并建立气相色谱测定工作场所空气中甲基异戊基甲酮的分析方法。方法采用活性炭吸附空气中的甲基异戊基甲酮气体,样品经二硫化碳解吸,FFAP毛细管柱分离,氢火焰离子化检测器检测,用气相色谱法测定,以保留时间定性,峰面积定量。结果甲基异戊基甲酮检出限为0.030μg/ml,检测值为0.030μg/ml^6 000μg/ml,平均解吸效率为95.91%,吸附容量为18.35 mg,10 d内稳定效率为95.04%,试验条件下能够将甲基异戊基甲酮与工作场所空气中可能存在的苯、甲苯、二甲苯(邻二甲苯、间二甲苯、对二甲苯)、乙苯、正己烷、丙酮、丁酮、甲基异丁基酮等干扰物分离。结论本方法操作简便易行,准确度和精密度高,结果可靠,各项指标均符合《职业卫生标准制定指南》中第4部分《工作场所空气中化学物质测定方法》的要求,可用于工作场所空气中甲基异戊基甲酮浓度的测定。Objective To study and establish a method for determination of methyl isoamyl ketone（ MIAK） in workplace air by gas chromatography（ GC）. Methods The methyl isoamyl ketone air samples were collected through charcoal adsorbent,desorbed with carbon disulfide,separated by FFAP capillary column,and then determined by GC with a flame ionization detector（ FID）. The retention times were used for qualitative analysis and the peak area was used for quantification analysis.Results The detection limit for the whole method of MIAK was 0. 030 μg/ml. The detection range was 0. 030 μg/ml-6 000 μg/ml. The desorption efficiency was 95. 91%. Breakthrough volume was 18. 35 mg. The storage efficiency in 10 days was 95. 04%. MIAK was well separated from probable interferences,such as benzene,toluene,xylene（ ortho-xylene,m-Xylene,para-xylene）,ethylbenzene,n-Hexane,acetone,butanone,methyl isobutyl ketone through the analytical procedure. Conclusion The method exhibited easy operation,good precision and accuracy. The results were reliable. The method met the requirements of The Determination Method of Chemical Substances in Workplace Air in GBZ/T 210. 4—2008,and can be used to determine MIAK in the air of workplace.

关 键 词：甲基异戊基甲酮 气相色谱 活性炭管 溶剂解析 

分 类 号：R134[医药卫生—劳动卫生]