静注小剂量肝素佐治小儿重症肺炎的应用  

Application of Low-Dose Heparin in the Adjuvant Treatment of Children with Severe Pneumonia

作　　者：钟活志[1] 叶永芝 贺道机[1] 吕波[1] ZHONG Huozhi, YE Yongzhi, HE Daoji, LV Bo(PICU, Zhaoqing First People ＇s Hospital, Zhaoqing 526000, Chin)

机构地区：[1]广东省肇庆市第一人民医院PICU,广东肇庆526000

出　　处：《临床医学工程》2018年第3期301-302,共2页Clinical Medicine & Engineering

基　　金：肇庆市科技创新指导类项目(项目编号:2015040305-7)

摘　　要：目的探讨静注小剂量肝素佐治小儿重症肺炎的效果。方法选取在我院PICU收治的重症肺炎患儿80例,随机分为对照组和治疗组各40例。对照组给予抗感染、雾化及支持综合治疗,视病情使用强心、抗炎、平喘治疗,治疗组在对照组基础上静注肝素钠10 IU/kg,每日1次,连用5日。比较两组患儿的血气分析指标、炎性指标、凝血功能及疗效。结果治疗组治疗后的血气分析指标、炎性指标、总有效率均明显优于对照组(P<0.05),凝血功能无异常。结论静注小剂量肝素佐治小儿重症肺炎的效果明显,具有临床推广价值。Objective To explore the effect of low-dose heparin in the adjuvant treatment of children with severe pneumonia. Methods 80 cases of children with severe pneumonia admitted to PICU of our hospital were selected and randomly divided into control group and treatment group, with 40 cases in each group. The control group received comprehensive treatment of anti-infection, atomization and support, and received cardiac, anti-inflammatory and antiasthmatic depending on the situation, while the treatment group received 10 IU/kg of heparin sodium on the basis of the control group once a day for 5 days. The blood gas analysis indicators, inflammatory indicators, blood coagulation function and curative effect were compared between the two groups. Results The blood gas analysis indicators, inflammatory indicators and total effective rate after treatment of the treatment group were significantly better than those of the control group （P 〈0.05）, and blood coagulation function had no abnormality. Conclusions Low-dose heparin in the adjuvant treatment of children with severe pneumonia has significant effect and clinical promotion value.

关 键 词：小剂量肝素 佐治 小儿重症肺炎 

分 类 号：R725.6[医药卫生—儿科]