肾移植后发生红细胞增多症与内源性促红细胞生成素水平变化的相关性  被引量:2

Variation of EPO and PET in Pre and Post-transplantaion

作  者:石峰[1] 马麟麟[2] 汤勇 吴国权 张玉海 袁之敏 

机构地区:[1]首都医科大学附属北京友谊医院泌尿科 [2]空军总医院泌尿科,北京100036

出  处:《空军总医院学报》2000年第1期30-32,共3页Journal of General Hospital of Air Force,PLA

摘  要:目的 :肾移植术后发生红细胞增多症 (PTE)与内源性促红细胞生成素 (EPO)动态变化的相关性。 方法 :分别测定血透析和肾移植病例 5 5名。将病人按移植前是否接受 EPO治疗 ,分为 EPO治疗组和非治疗组。动态观察手术前后 EPO变化过程。比较治疗组和非治疗组的差异与血象变化。 结果 :两组各观察点 EPO实测值差异无显著性。 EPO治疗组术后可见两次 EPO升高高峰 ,分别为 32 IU / L和 2 1IU / L。贫血的不受 EPO变化的影响 ,呈稳定上升趋势 ,第 2 1天两组血红蛋白平均达到 90 g/ L ,平均术后 8d肾功能达到正常。肾功能延迟恢复病例 ,二次 EPO水平升高过程欠缺。用与未用 EPO组血象变化相同。术后监测 EPO水平 ,有助于预测和判断发生 PTE的相关性。Objective Researching the relation between the variant tendency of inherent erythropoietin (EPO) and the peripheral blood after renal transplanted. Method Checking the lever of EPO in 55cases who were receiving hemodialysis (HD) or the renal transplantation(Trans.). Dividing the patients into the groups: HD and trans. According to the method that they had received. Comparing the result of tow groups in EPO and the blood. Result The levers of EPO is not very difference in towgroups. There are tow peaks in EPO treated group posttransplanted. The coursc of correcting anemia did not been influenced by the variation of EPO.The hemoglobin rose smoothly. The renal function recovered after 8 days. The patients who were renal function delayed recovery dose not observed seconed peak of EPO. Conclusion The anemia will recover to the norml lever following the function of graftresurrection grandly after the operation.The change of the peripheral blood was the same in two groups. Checking the EPO lever is conducive to judge the condition of the kidney and to forecast the PET.

关 键 词:相关性 肾移植 红细胞增多症 红细胞生成素 术后 

分 类 号:R699.2[医药卫生—泌尿科学] R555.1[医药卫生—外科学]

 

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