微量免疫荧光试验诊断呼吸道肺炎衣原体急性感染  

Diagnosis of acute infection of chlamydia pneumonia among patients with respiratory diseases by microimmunofluorescence test

作　　者：李建标[1] 王颖[1] 赵建中[2] 纪树国[2] 朱美财[1] 

机构地区：[1]空军总医院临床实验科,北京100036 [2]空军总医院呼吸内科,北京100036

出　　处：《空军总医院学报》2000年第1期38-39,共2页Journal of General Hospital of Air Force,PLA

摘　　要：目的 :探讨肺炎衣原体 (Cpn)急性感染在呼吸道疾病中的重要性。　方法 :用微量免疫荧光试验检测血清中 Cpn抗体 Ig G。　结果 :35 .5 %呼吸道疾病存在 Cpn急性感染。在肺炎组抗体 (效价≥ 5 12 )阳性率为 47.6 % ,提示 1998年至 1999年可能处在北京市 Cpn流行期 ;在哮喘组的阳性率达到 5 0 % ;在肺心病组和肺癌组的阳性率分别为 5 0 .0 %和 2 6 .3%。　结论 :检测 Cpn抗体 Ig G有助于对 Cpn急性感染进行确诊 ,从而指导临床用药。Objective To evaluate the role of acute infection of Chlamydia pneumonia (Cpn) in respiratory diseases Methods Microimmunofluorescence test for detection of IgG antibodies for Cpn in serum was used. Results Acute Cpn infection was diagnosed in 35.5% of the respiratory diseases. Antibodies for Cpn(titer of ≥512)were present in 47.6% of the pneumonia group, which may suggest that during 1998 to 1999, Cpn caused a epidemic in Beijing. They were also present in 50% of asthma group, 50.0% of pneumocardial disease group and 26.3% of lung cancer group. Conclusions Detection of antibodies for Cpn conduce to diagnosis of acute Cpn infection and determination of appropriate therapy.

关 键 词：微量免疫荧光试验 诊断 衣原体感染 呼吸道疾病 荧光免疫测定 

分 类 号：R518[医药卫生—内科学] R446.61[医药卫生—临床医学]