傅里叶域光学相干层析成像技术的研究进展  

Research Progress in Fourier Domain Optical Coherence Tomography

作　　者：李培[1] 杨姗姗[1] 丁志华[1] 李鹏[1] Li Pei, Yang Shanshan, Ding Zhihua, Li Peng(State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering Zhejiang University, Hangzhou, Zhejiang 310027, Chin)

机构地区：[1]浙江大学现代光学仪器国家重点实验室光电科学与工程学院,浙江杭州310027

出　　处：《中国激光》2018年第2期147-157,共11页Chinese Journal of Lasers

基　　金：国家自然科学基金(61475143;11404285;61335003;61327007);国家863计划(2015AA020515);中央高校基本科研业务费专项资金(2017QNA5004);教育部留学回国人员科研启动基金;浙江省科技厅公益技术研究社会发展项目(2015C33108)

摘　　要：光学相干层析成像(OCT)可以实现生物组织内部微观结构的实时、高分辨率、三维成像,在临床诊疗与基础科学研究领域得到了广泛的应用。近年来,得益于光源与探测技术的发展,傅里叶域OCT已经成为OCT的主流模式,尤其推动了OCT微血管造影等功能成像技术的发展。以傅里叶域OCT为重点,回顾了OCT的工作原理,阐述了系统主要的性能参数及其影响因素,介绍了傅里叶域OCT在成像量程、成像速度以及功能成像方面的现状并对OCT的研究作了展望。Optical coherence tomography（OCT）enables three-dimensional internal micro-structural imaging of biological tissue in real time with high resolution,and it has wide range of applications in clinic diagnosis,treatment and basic scientific research.In recent years,thanks to the development of light sources and detection technology,Fourier domain OCT has become the mainstream OCT model,particularly has promoted the development of functional imaging technology,such as OCT microangiography.In this work,we review the principle of OCT based on Fourier domain OCT,and illustrate the primary performance parameters and their influence factors of system.The recent advances and expectations in imaging range,speed and functional extensions are introduced.

关 键 词：医用光学 光学相干层析 功能成像 

分 类 号：TN247[电子电信—物理电子学]