高光谱成像技术在生物医学中的应用进展  

Recent Advances of Hyperspectral Imaging Application in Biomedicine

作　　者：刘立新 李梦珠[1] 赵志刚 屈军乐[2] Liu Lixin1,2, Li Mengzhu1, Zhao Zhigang2, Qu Junle2(1School of Physics and Optoelectronic Engineering, Xidian University, Xi＇an, Shaanxi 710071, China; 2 Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong 518060, Chin)

机构地区：[1]西安电子科技大学物理与光电工程学院,陕西西安710071 [2]深圳大学光电工程学院深圳大学光电子器件与系统教育部/广东省重点实验室,广东深圳518060

出　　处：《中国激光》2018年第2期208-217,共10页Chinese Journal of Lasers

基　　金：国家自然科学基金(61378091);宁波市自然科学基金(2016A610032);深圳大学光电子器件与系统教育部/广东省重点实验室开放基金(GD201711);中央高校基本科研业务费项目(NSIY051405);高等学校学科创新引智计划(B17035)

摘　　要：高光谱成像技术(HSI)是将成像技术和光谱技术相结合的多维信息获取技术,具有图谱合一的重要特征。通过HSI获得的空间分辨光谱成像提供了关于组织生理学,形态学和组成的诊断信息。HSI是医学应用的新兴成像模式,在生物医学领域,特别是在疾病诊断和图像引导手术中,具有极广阔的应用前景。介绍了HSI的基本原理、系统的基本构成及特点,总结和阐述了近年来HSI在生物医学领域的发展及其在疾病诊断和手术指导中的应用进展。指明该技术领域今后的重点研究方向,并对其发展前景进行了分析和展望。Hyperspectral imaging（HSI）combines spectroscopy and imaging technology,and can acquire multidimensional information that includes two-dimensional spatial information and one-dimensional spectral information.The space-resolved spectral images obtained by HSI can provide diagnostic information about histophysiology,morphology,and composition of tissues.HSI is an emerging medical imaging modality and has broad potential applications in the field of biomedicine,especially in disease diagnosis and image-guided surgery.We introduce the basic principles of HSI,the configuration and characteristics of HSI system,and review the recent developments of HSI in biomedical field and its applications in disease diagnosis and surgical guidance.The future research direction and development prospects of HSI are also analyzed and forecasted.

关 键 词：医用光学 高光谱成像 疾病诊断 癌症 图像引导手术 

分 类 号：O439[机械工程—光学工程]