偏振频域OCT系统光谱错位分析及光谱校准  

Wavelength Misalignment Analysis and Spectral Calibration for Fourier Domain Polarization-Sensitive Optical Coherence Tomography

作　　者：陈艳[1,2] 李中梁 南楠[1] 步扬 卢宇[1,2] 宋思雨[1,2] 王向朝 Chen Yan1,2, Li Zhongliang1,2, Nan Nan1, Bu Yang1,2, Lu Yu1,2, Song Siyu1,2, Wang Xiangzhao1,2(1Laboratory of Information Optics and Opt-Electronic Technology, Shanghai Institute of Optics and Fine Mechanics Chinese Academy of Sciences, Shanghai 201800, China ; ZUniversity of Chinese Academy of Sciences, Beijing 100049, Chin)

机构地区：[1]中国科学院上海光学精密机械研究所信息光学与光电技术实验室,上海201800 [2]中国科学院大学,北京100049

出　　处：《中国激光》2018年第2期259-267,共9页Chinese Journal of Lasers

基　　金：上海市科学技术委员会创新行动计划(15441905600);广西高校光电信息处理重点实验室开放基金资助项目(KFJJ2016-04)

摘　　要：偏振频域光学相干层析成像(FD-PS-OCT)可以通过测量样品的偏振特性实现某些疾病的早期诊断。偏振参数的测量精度关系到疾病诊断的准确性。在FD-PS-OCT中,正交的两路干涉信号即使仅存在很小的光谱错位,也可能导致偏振参数计算结果产生较大的误差。光谱校准是提高偏振参数测量精度的前提,而在进行光谱校准之前,有必要明确光谱错位对偏振参数计算精度的影响。通过理论分析和仿真计算,深入分析了光谱错位与偏振参数计算误差之间的关系。在此基础上,提出了一种光谱校准方法,该方法通过判断已知样品延迟量和快轴方位角的误差大小来实现光谱缩放和平移的校准。最后进行了波片测量实验,验证了该方法的有效性,证明了误差分析的正确性。Fourier domain polarization-sensitive optical coherence tomography（FD-PS-OCT）can measure the polarization properties of a sample to provide early diagnosis for some diseases.The accurate diagnosis is required to measure the polarization parameters in a high accuracy.However,the accuracy is greatly affected by wavelength misalignment.Even a slight wavelength mismatch in FD-PS-OCT will result in nonnegligible polarization artifacts.So an accurate wavelength assignment is necessary.In order to decrease the polarization error and improve the accuracy of spectral calibration,the effect of the wavelength misalignment on the polarization parameters calculation should be clear.An analysis is performed on the relationship between the wavenumber misalignment and the calculated error in theory and simulation.Based on the error analysis,a spectral calibration method is proposed.The method achieves the wavelength alignment through evaluating the retardation and fast axis orientation errors.The wave plate experiments show the good performance of the method and the reasonability of the error analysis.

关 键 词：生物光学 光学相干层析成像 偏振 光谱校准 误差分析 

分 类 号：O436[机械工程—光学工程]