吸烟与大气污染对肺部疾病的影响  

Influence of smoking and air pollution on lung diseases

作　　者：高欣丽 张英杰[1] 樊磊[1] 王晓波[1] Gao Xinli , Zhang Yingjie, Fan Lei, Wang Xiaobo.(Department of Pharmacy, Chinese People＇s Liberation Army 210th Hospital Pharmacy, Dalian 116015, Chin)

机构地区：[1]中国人民解放军第二一0医院药剂科,大连116015 [2]大连医科大学,116044

出　　处：《国际呼吸杂志》2018年第5期378-381,共4页International Journal of Respiration

摘　　要：环境污染是我国现在面临的一个主要问题，大气细颗粒物（PM2.5）由于其潜在的生物蓄积和氧化损伤被列为重要的空气污染物，可影响人类许多不同的系统和器官。研究发现PM2.5可引起哮喘，呼吸道炎症，危害肺功能，甚至促进癌症的发生，对呼吸系统有严重的损害。该文对PM2.5的组成、理化性质、主要致病机制以及对肺部疾病影响的研究现况作一综述。Environmental pollution is a major problem now in our country. Due to the potential bioaccumulation and oxidative damage, atmospheric fine particulate matter （PM2.5） is classified as an important air pollutant and can affect many different systems and organs of humans. Many studies found that PM2.5 could cause asthma and respiratory inflammation, endanger lung function, seriously damage the respiratory system, and even promote the occurrence of cancer. This article reviews the composition, physicochemical properties, main pathogenic mechanism of PM2.5 and the impact of PM2.5 on pulmonary diseases.

关 键 词：空气污染 吸烟 肺部疾病 

分 类 号：R563[医药卫生—呼吸系统]