MMT/FeCl_3催化下微波法合成双吲哚甲烷衍生物  

Synthesis of bis (indol-3-yl) methanes catalyzed by MMT/FeCl_3 under microwave irradiation

作　　者：王文琛[1] 杨志翔[1] 王金娟[1] 尹晓刚[1] 陈治明[1] WANG Wen-cheng, YANG Zhi-xiang, WANG Jin-juan, YIN Xiao-gang, CHENG Zhi-ming(Key Laboratory of Functional Materials Chemistry of Guizhou Province, School of Chemistry and Materials Science, Guizhou Normal University, Guiyang 550001, Chin)

机构地区：[1]贵州师范大学化学与材料科学学院贵州省功能材料重点实验室,贵州贵阳550001

出　　处：《云南大学学报（自然科学版）》2018年第2期341-346,共6页Journal of Yunnan University(Natural Sciences Edition)

基　　金：国家自然科学基金(21362006);贵州省自然科学基金(黔科合J字[2009]2021)

摘　　要：探究一种微波辅助MMT/FeCl_3催化吲哚与芳香醛的反应,方便、快速地合成双吲哚甲烷衍生物.研究表明,在CH_2Cl_2中,微波辅助x=15%MMT/FeCl_3催化,产率最高可达94%.催化剂重复使用4次,产率仍可达60%.该方法具有操作简单、反应快、产率高、环境友好等优点,为合成双吲哚甲烷衍生物提供了一条有效途径.A rapid and efficient microwave-assisted method for the synthesis of bis（ indol-3-yl） methane by the reaction of indoles with aromatic aldehyde catalyzed by Montmorillonite FeCl_3 has been developed. The reaction was efficiently performed in the presence of MMT/FeCl_3（ x = 15% ） in CH_2Cl_2 with high yield up to 94% .The catalyst was reused 4 times and the yield was still up to 60 % .This protocol has the advantages of simple operation,short reaction times,high yields and environmental friendliness,the method is the efficient approach for the synthesis of bis（ indol-3-yl） methanes.

关 键 词：吲哚 芳香醛 双吲哚甲烷衍生物 催化 微波辅助 

分 类 号：O626[理学—有机化学]