中药足浴对糖尿病周围神经病变干预作用研究进展  

Research Progress on the Intervention Effect of Chinese Medicine Foot Bath on Diabetic Peripheral Neuropathy

作　　者：符宇[1] 范冠杰[2] 段力[1] 林玉平[2] 黄皓月[2] FU Yu1 , FAN Guanjie2, DUAN Li1 , LIN Yuping2 , HUANG Haoyue2(1. Guangzhou University of Chinese Medicine, Guangzhou Guangdong China 510000; 2. Guangdong Provincial Hospital of Chinese Medicine, Guangzhou Guangdong China 51000)

机构地区：[1]广州中医药大学,广东广州510000 [2]广东省中医院,广东广州510000

出　　处：《中医学报》2018年第2期218-222,共5页Acta Chinese Medicine

基　　金：国家科技支撑计划课题(2015BAI04B09)

摘　　要：中药足浴防治DPN疗效较好,尤其是温经通络、活血化瘀的组方。但目前大部分临床研究多为小样本、非随机对照的观察性研究,设计欠严谨,循证医学证据级别较低,适应证、禁忌证等未进行规范化研究,治疗DPN的内在机制不明确。首先,今后的研究应通过建立DPN动物模型进行体内外实验研究,明确其内在作用机制。其次,利用现代流行病学和循证医学的方法对中药足浴治疗DPN进行规范化临床疗效评价,开展多中心、双盲、随机、对照研究,提升循证医学的证据级别。Traditional Chinese medicine foot bath is effective in preventing and treating diabetic peripheral neuropathy（DPN）,especially the prescription of warming meridian and clearing collaterals and activating blood circulation and removing blood stasis.However,most of the researches were observational studies of small samples and non-randomized controlled,lack of rigorous design,lower level of evidence of evidence-based medicine,indications and contraindications were not standardized,and the underlying mechanism for the treatment of DPN was unclear.The future research should be carried out in vivo and in vitro experimental research through the establishment of DPN animal model to clarify its internal mechanism.Secondly,we use modern epidemiology and evidence based medicine to standardize the clinical efficacy evaluation of TCM foot bath in the treatment of DPN,and carry out a multicenter,double-blind,randomized controlled study to enhance the evidence level of evidence based medicine.

关 键 词：糖尿病周围神经病变 中药足浴 中医疗法 

分 类 号：R259.872[医药卫生—中西医结合]