抗生素浸润导管应用于脑积水分流术的临床研究  

Clinical application of antibiotic-impregnated shunt catheters in hydrocephalus shunt

作　　者：熊学辉[1] 瞿丹霞 魏小川[1] 罗杰[1] 樊俊 黄明火 XIONG Xuehui, QU Danxia, WEI Xiaochuan, LUO Jie, FAN Jun, HUANG Minghuo.(Huanggang central hospital, Huanggang, 438000, China.)

机构地区：[1]湖北省黄冈市中心医院神经外科,黄冈438000

出　　处：《中国神经精神疾病杂志》2017年第12期728-731,共4页Chinese Journal of Nervous and Mental Diseases

摘　　要：目的评估抗生素浸润导管应用于脑积水分流术的临床疗效。方法回顾分析2011年5月至2016年8月在我院接受过脑积水分流术患者资料,依照其使用导管类型不同将其分为普通导管组(非AISCs组)及抗生素浸润导管组(AISCs组)。所有患者在分流手术后随访6个月,对分流感染情况进行统计。结果最终获取193例接受脑积水分流手术的患者资料,其中非AISCs组124例、AISCs组69例。非AISCs组术后感染率13.71%,分流管堵塞率8.87%,再次手术发生率5.65%;AISCs组术后感染率2.90%,分流管堵塞率5.80%,再次手术发生率4.35%。与非AISCs组相比,AISCs的术后感染发生率显著降低(P<0.05),分流管堵塞及再次手术发生率相比未见显著差异(P>0.05);此外,两组患者在分流管断裂、移位、外露方面均未见显著差异性(P>0.05)。结论 AISCs可以有效降低脑积水分流感染的发生率。Objective To evaluate the clinical efficacy of antibiotic-impregnated shunt catheters in hydrocephalus shunt. Methods A retrospective analysis of clinical data from patients with hydrocephalus shunt surgery in our hospital during the period from May 2011 to August 2016. Based on the types of catheters, patients were divided into common conduit （not AISCs group） and antibiotics infiltrating pipe groups （AISCs group）. All patients were followed up for 6 months after shunt surgery. The diversion and infection was recorded. Results The data of 193 patients with hydrocephalus shunt were analyzed, including 124 cases of non-AISCs group and 69 cases of AISCs group. Compared with non-AISCs group, the incidence of postoperative infection of AISCs was significantly decreased （P〈0.05）. There was no significant difference in the incidence of shunt and reoperation between the two groups （P〉0.05）. In addition, there was no significant difference in the rupture, displacement and exposure of the two groups （P〉0.05）. Conclusion ASICs can effectively reduce the incidence of hydrocephalus shunt infection.

关 键 词：抗生素浸润导管 脑积水 分流 感染 

分 类 号：R651.1[医药卫生—外科学]