疏风解毒胶囊联合环丙沙星与维生素C治疗肺风粉刺的临床观察  

Contains Polygonum cuspidatum of Shufeng Capsules with Vit C for treatment clinical observation of lungs and acne.

作　　者：陈惠阳[1] 周星[1] 何洢博 刘寿全[1] CHEN Hui-yang, ZHOU Xing, HE Yi-bo, LIU Shou-quan(Beijing Sixth Hospital of Dermatology, Beijing 100007, Chin)

机构地区：[1]北京市第六医院皮肤科,北京100007

出　　处：《药物评价研究》2017年第12期1787-1789,共3页Drug Evaluation Research

摘　　要：目的评价疏风解毒方联合环丙沙星与维生素C治疗肺风粉刺的临床疗效和愈后。方法将60例痤疮中医辨证为肺经风热型的患者随机分成治疗组与对照组各30例,对照组给予外用盐酸环丙沙星和口服Vit C,治疗组在对照组的基础上同时给予疏风解毒胶囊,两组疗程均为1个月。两组分别在治疗2、4周时评价系统症状(口干、便秘等)和皮损炎症好转情况、新发皮损情况、愈后(出现色素沉着和凹陷性瘢痕)情况、临床总有效率,同时考察两组不良反应以评价其安全性。结果两组治疗后临床疗效对比,治疗组总有效率为96.67%高于对照组的76.67%(P<0.05)。治疗两周后,治疗组口渴、便秘等系统症状减轻例数、皮损处红肿消退例数分别为26例、24例,对照组为4例、7例,治疗组的症状减轻人数明显多于对照组,差异有显著统计学意义(P<0.01);且两周后治疗组有新发皮损数明显少于对照组,差异有显著统计学意义(P<0.01)。结论疏风解毒方联合环丙沙星与维生素C在治疗痤疮肺经风热证上疗效显著,愈后理想。Objective To evaluate the clinical efficacy and prognosis of the treatment of pulmonary air acne combined with the treatment of Typhopus Decoction and Vit C. Methods Sixty patients with acne vulgaris were randomly divided into treatment group and control group. The control group was treated with Ciprofloxacin Hydrochloride and Vit C. The treatment group was treated on the basis of the control group Given Shufeng Jiedu Capsules, two groups of treatment are one month. Results The total effective rate was 96.67% in the treatment group compared with 76.67%（P〈0.05） in the control group. Conclusion Shufeng Jiedu Capsules combined with Vit C have the significant effect and more ideal in the treatment of acne vulgaris by wind and heat syndrome.

关 键 词：虎杖 疏风解毒 维生素C 肺风粉刺 

分 类 号：R969.4[医药卫生—药理学]