生化检验项目在肝硬化患者中的变化特点  

Application of biochemical tests in the diagnosis of cirrhosis

作　　者：陈春燕[1] 丁昱方 夏正君 张泽君[1] CHEN Chunyan,DING Yufang,XIA Zhengjun,et al.(Dazhou Integrative Medicine Hospital, Sichuan Province, Dazhou 635000, Chin)

机构地区：[1]四川省达州市中西医结合医院,635000

出　　处：《临床合理用药杂志》2018年第7期25-25,28,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的分析生化检验项目在肝硬化疾病中的变化特点。方法选取2016年5月-2017年5月来医院就诊的肝硬化患者52例,将其设为观察组,同时选择同时期在我院接受体检的正常体检者52例设为对照组,比较2组的生化检验结果和纤维化指标。结果观察组患者的ALT、AST、ALP、TBIL、DBIL、γ-GT指标水平均明显高于对照组,ALB、CHE、TP和A/G指标水平均明显低于对照组,差异均有统计学意义(P<0.05)。观察组患者的HA、LN、PC-Ⅲ和Ⅳ-C水平均明显高于对照组,差异均有统计学意义(P<0.05)。结论肝硬化患者的部分生化指标和正常人有很大的差异,因此可通过生化检验项目为肝硬化的诊断提供重要的参考。Objective To investigate the application value of biochemical tests in the diagnosis of cirrhosis. Methods52 patients with cirrhosis who came to the hospital from May 2016 to May 2017 were selected as observation group,at the same time selected the same period in hospital to accept the physical examination of 52 cases of normal physical examination as control group. The biochemical test results and fibrosis indexes of two groups were compared. Results The levels of ALT,AST,ALP,TBIL,DBIL and γ-GT in observation group were significantly higher than those in control group,the levels of ALB,CHE,TP and A/G in observation group were significantly lower than those in control group,the differences were statistically significant（ P〈0. 05）. The levels of HA,LN,PC-Ⅲ and Ⅳ-C in observation group were significantly higher than those in control group,with statistical significance（ P〈0. 05）. Conclusion The biochemical parameters of the patients are very different from those of the normal subjects,so biochemical tests can be used to provide an important reference for the diagnosis of cirrhosis.

关 键 词：生化检验项目 肝硬化疾病 诊断 

分 类 号：R446.1[医药卫生—诊断学] R575.2[医药卫生—临床医学]