吉米沙星治疗急性细菌感染的临床研究  

Randomized and parallel clinical trial of Gemifloxacin tablets in acute bacterial infection

作　　者：李宏力[1] 张丽红[1] 李湘 王萍[2] 张鹏[2] Li Hong - li1 , ZHANG Li - hong1 , LI Xiang2, WANG Ping2, ZHANG Peng2(1. Department of Nursing, Shaanxi Energy Institute, Xianyang 712000, China; 2. Xi ＇an Northern Hospital, Xi＇ an 710213, Chin)

机构地区：[1]陕西能源职业技术学院护理系,陕西西安710613 [2]西安北方医院,陕西西安710213

出　　处：《陕西能源职业技术学院学报》2017年第2期53-55,共3页

摘　　要：目的评价吉米沙星片治疗敏感菌引起的急性感染的疗效及安全性。方法将50名不同细菌导致的急性细菌感染患者采用随机对照、平行开放的实验设计分为两组，试验组给予吉米沙星片，用法用量为320mg，qd，口服，对照组给予左氧氟沙星片，用法用量为500rag，qd，口服，疗程均为7—14天。结果试验组和对照组的临床有效率分别为81．08％和57．77％；不同细菌感染细菌清除率分别为91．3％和79．16％；不良反应发生率分别为4％和8％。结论吉米沙星对于急性细茵感染疗效高，且具有安全性。Objective To evaluate the efficacy and safety of Gemifloxacin tablets in the acute infection caused by sensitive bacteria. Methods Fifty acute infection patients by bacteria was divided into two groups by using randomized, parallel open experimental design. The tested group was gave Gemifloxacin tablets 320 mg, oral qd, at the same time the controlled group was gave levofloxacin 500 mg, qd, oral, Period of treatment were 7 - 14 days. Results Clinical effectiveness of the tested group and the control group were 81.08% and 57.77% ;Bacterial clearance rate were 91.3% and 79.16% respectively;The incidence of adverse reactions were 4% and 8% respectively. Conclusion The effect of Gemifloxacin has safety and effectiveness for different acute bacterial infection.

关 键 词：吉米沙星 左氧氟沙星 急性细菌感染 

分 类 号：R515[医药卫生—内科学]