基于2013-2015年无偿献血者抗-HCV筛查情况估算深圳市宝安区一般人群抗-HCV阳性率  

Anti-HCV prevalence in general population in Baoan district of Shenzhen,2013-2015

作　　者：饶展宏 詹志强[1] 涂玉山[1] 孙群露[1] 郝元涛[2] RAO Zhan-hong1, ZHAN Zhi-qiang1, TU Yu-shan~, SUN Qun-lu1, HAO Yuan-tao2(1.Baoan District Center for Disease Control and Prevention, Shenzhen , Guangdong 518100 ; 2.School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510080, Chin)

机构地区：[1]深圳市宝安区疾病预防控制中心,广东深圳518100 [2]中山大学公共卫生学院,广东广州510080

出　　处：《热带医学杂志》2018年第3期400-404,共5页Journal of Tropical Medicine

基　　金：2016年深圳市宝安区科技计划项目(2016CX232)

摘　　要：目的了解深圳市宝安区2013-2015年无偿献血者丙型肝炎病毒(HCV)感染流行情况,据此估算宝安区一般人群抗-HCV阳性率。方法收集宝安区中心血站2013-2015年无偿献血者一般人口学特征、抗-HCV检测结果资料,对无偿献血者HCV感染流行情况进行统计分析,采用"比率法"基于无偿献血者抗-HCV阳性率估算一般人群抗-HCV阳性率。结果 2013-2015年无偿献血者抗-HCV筛查分别为30 150、30 771和30 276人,抗-HCV阳性率分别为0.33%、0.26%和0.28%。不同性别、年龄、年份阳性率比较差异无统计学意义(P>0.05)。据此估算宝安区一般人群抗-HCV阳性率范围为0.36%~1.12%或0.36%~0.62%。结论基于无偿献血者抗-HCV阳性率估算的宝安区一般人群抗-HCV阳性率表明宝安区为丙肝感染低流行区。Objective To investigate the prevalence of anti-HCV among blood donors in Baoan district from 2013 to 2015, and estimate the prevalence of anti-HCV in general population of this region based on the data obtained from blood donors. Methods Information on the demographics and test results of the anti-HCV were collected. Chi-squared test was used to compare the positive rates of anti-HCV across different groups. The prevalence of anti-HCV in general population was estimated based on such information by using the ratio method. Results Between 2013 to 2015, the number of positive for anti-HCV in blood donors was 30 150, 30 771 and 30 276, respectively, with the corresponding positive rates of 0.33%, 0.26% and 0.28%, respectively. The difference of anti-HCV positive rate showed in sex, age and different years had no statistically significant （P〉0.05）. It was estimated that the positive rate of anti-HCV in general population of Baoan district ranged from 0.36% to 1.12% or 0.36% to 0.62%. Conclusion The prevalence of anti-HCV among general popula- tion estimated by blood donors suggests that Baoan district was low prevalence area of HCV infection.

关 键 词：无偿献血者 一般人群 抗-HCV阳性率 

分 类 号：R512.63[医药卫生—内科学]