盐酸坦索罗辛在老年男性混合痔患者围手术期的应用  

The Application of Tamsulosin Hydrochloride in the Perioperative Period in Elderly Men with Hemorrhoids

作　　者：黄淑娟[1] 叶辉[2] 李春玉[1] 唐雪莲[1] Huang Shujuan1 , Ye Hui2., Li Chunyu1, Tang Xuelian1(1 Department of Geriatrics, Jingzhou Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jingzhou 434000, China 2 Department of Anorectal Surgery, Jingzhou Hospital, Tongji Medical College, Huazhong University of Science and Technology Jingzhou 434000, Chin)

机构地区：[1]华中科技大学同济医学院附属荆州医院老年医学科,中国荆州434000 [2]华中科技大学同济医学院附属荆州医院结直肠肛门外科,中国荆州434000

出　　处：《国际老年医学杂志》2018年第2期57-59,共3页International Journal of Geriatrics

基　　金：湖北省卫计委项目(WJ2017S016);荆州市科技局项目(2015058)

摘　　要：目的探讨盐酸坦索罗辛在老年男性混合痔患者围手术期应用的临床价值。方法收集2015年4月～2017年4月在我院行混合痔手术治疗的老年男性患者临床资料，共138例。根据随机分组方法将其分为实验组和对照组，各69例。实验组在手术前1d、术后4h、术后第1d及术后第2d睡前分别给予盐酸坦索罗辛0．2mg口服；对照组于相应时间点给予安慰剂口服。观察两组患者术后尿潴留、VAS疼痛评分及满意度的差异。结果实验组平均年龄（69．07±5．65）岁，平均手术时间（23．30±5．03）min，外剥内扎术21例，内痔痔上黏膜环切钉合术48例，术后使用镇痛泵20例；对照组平均年龄（69．71±6．21）岁，平均手术时间（22．01±4．74）min，外剥内扎术19例，内痔痔上黏膜环切钉合术50例，术后使用镇痛泵16例。上述各指标两组间比较差异无统计学意义（P〉0．05）。实验组术后尿潴留10例，VAS疼痛评分（2．71±1．27）分，满意度（2．54±0．58）分；对照组术后尿潴留39例，VAS疼痛评分（3．86±2．02）分，满意度（2．22±0．59）分。上述各指标比较差异均有统计学意义（P〈0．05）。结论围手术期口服盐酸坦索罗辛可以降低尿潴留的发生，减轻术后疼痛，提高患者满意度，在临床上具有一定的应用价值。Objective To explore the role of tamsulosin hydrochloride in perioperative period in elderly men with hemor- rhoids. Methods 138 Elderly men undergoing hemorrhoids surgery were randomly divided into the control group and the experimental group in our hospital from April 2015 to April 2017. The experimental group was given 0. 2 mg of tamsulosin hydroehloride orally the night before surgery, 4 h and the night of the first and second day after surgery. The control group was given a placebo orally at the corresponding time point. The differences of urinary retention, VAS pain score and satisfaction were compared between the two groups. Results In the experimental group, the average age was （69. 07± 5.65） years, the operation time was （23. 30 ± 5.03 ） min, the number of cases undergoing Milligan - Morgan, procedure for prolapse and hemorrhoids （PPH） and using analgesia pump after operation were 21, 48 and 20 respectively. In the control group, the average age was （69.71±6. 21 ） years, the operation time was （22. 01 ±4. 74） rain, the number of cases undergoing Milligan - Morgan, PPH and using analgesia pump after operation were 19, 50 and 16 respectively. There was no significant difference between the two groups （P 〉 0. 05 ）. In the experimental group, there were 10 cases of urinary retention, the VAS pain score was （2. 71 ± 1.27） and the satisfaction was （9. 54±0. 58）. In the controlgroup, there were 39 cases of urinary retention, the VAS pain score was （3.86± 2. 02） and the satisfaction was （2. 22 ±0. 59 ）. There were significant differences between the two groups （ P 〈 0.05 ）. Conclusion Perioperative use of tamsulosin hydrochloride may reduce the incidence of postoperative urinary retention, relieve postoperative pain and improve patient satisfaction in elderly men with hemorrhoids.

关 键 词：盐酸坦索罗辛 混合痔 围手术期 尿潴留 

分 类 号：R657.18[医药卫生—外科学]