单核细胞计数/高密度脂蛋白与急性冠状动脉综合征患者的相关性分析  

Monocytes/high-density lipoprotein cholesterol and correlation analysis in patients with acute coronary syndrome

作　　者：陈树鑫[1] 黄永洪 CHEN Shuxin1, HUANG Yonghong2(1Department of Emergency, the People＇s Hospital of Zhongshan City, Zhongshan, 528403, China;2Department of Paediatrics,the People＇s Hospital of Zhongshan Cit)

机构地区：[1]中山市人民医院急诊科,广东中山528403 [2]中山市港口医院内儿科

出　　处：《临床急诊杂志》2018年第2期121-123,共3页Journal of Clinical Emergency

摘　　要：目的:探讨单核细胞计数/高密度脂蛋白(MHR)在急性冠状动脉综合征(ACS)患者中的变化情况和临床意义。方法:选取2016-01-2017-02在中山市人民医院急诊科确诊为ACS的164例患者,作为研究组。选取同时期健康体检者154例作为对照组,用Sysmex-XN9000血球仪检测两组全血得出单核细胞计数,用罗氏Cobas8000全自动生化分析仪检测得出高密度脂蛋白(HDLC)、低密度脂蛋白(LDLC)、甘油三酯(TG)、载脂蛋白A1(apoA1)、载脂蛋白B(apoB1)、脂蛋白(a)(LPa)、尿酸(UA)的结果。结果:(1)ACS患者LDLC水平低于对照组,而MHR、HDLC、TG、apoA1、apoB1、TC、LPa水平均高于对照组,差异有统计学意义(P<0.05),M在两组比较中没有差异。(2)Logistic回归分析结果中,MHR、HDLC、TG、apoA1、apoB1、LPa等指标都是ACS患者的独立危险因子,差异有统计学意义(P<0.05)。结论:MHR和血脂指标与ACS密切相关,可作为ACS病情预测重要的指标。Objective：To explore the mononuclear cell count/high density lipoprotein（MHR）changes in patients with acute coronary syndrome and clinical significance.Method：Select between January 2016 and February2016 in zhongshan city people＇s hospital emergency department patients diagnosed with acute coronary syndrome（ACS）（164 cases）.Selected at the same time healthy physical examination as the control group（154 cases）,with Sysmex-XN9000 blood to test two groups of whole blood mononuclear cell count,with roche Cobas8000 high-density lipoprotein cholesterol（hdl-c）for the full automatic biochemical analyzer test（in HDLC）,low density lipoprotein（LDLC）,triglyceride（TG）,apolipoprotein A1（apoA1）,apolipoprotein B（apoB1）,lipoprotein（a）（LPa）,uric acid（UA）.Result：（1）In patients with acute coronary syndrome LDLC levels lower than the control group,while MHR,in HDLC,TG,apoA1,apoB1,TC,LPa level are higher than the control group,the difference was statistically significant（P〈0.05）,M comparing the two groups had no difference.（2）In the Logistic regression analysis results,MHR,in HDLC,TG,apoA1,apoB1,LPa is an independent risk factor for acute coronary syndrome patients,the difference was statistically significant（P〈0.05）.Conclusion：MHR and blood lipids index are closely associated with acute coronary syndrome,can be used as a prognostic indicator of important acute coronary syndrome（acs）.

关 键 词：单核细胞计数/高密度脂蛋白 急性冠状动脉综合征 相关性 

分 类 号：R541.4[医药卫生—心血管疾病]