2016～2017年深圳宝安区4056例孕前妇女TORCH感染现状及危险因素分析  

Analysis the current situation and risk factors of the TORCH infection of 4056 pregnant women in Shenzhen Baoan District from 2016 to 2017

作　　者：颜申姬 周慧[1] 房笃智 王敏 张玲 YAN Shen-ji, ZHOU Hui, FANG Duo-zhi, WANG Min, ZHANG Ling(Laboratory of People＇s Hospital of Shenzhen Baoan District, Guangdong Province, 518101)

机构地区：[1]深圳市宝安区人民医院检验科,广东518101

出　　处：《中国优生与遗传杂志》2018年第3期67-69,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的了解2016~2017年深圳宝安区18~35岁孕前妇女TORCH感染现状,并对感染危险因素进行调查分析,探讨其流行分布特征,为进一步诊断与防治TORCH感染提供依据。方法随机收集2016年2月~2017年8月来本院进行孕前优生筛查的18~35岁孕前妇女4056例,其中城镇2232例,乡村1824例,分别采用酶联免疫法(ELISA)检测其血清中风疹病毒IgG(RV-IgG),巨细胞病毒IgM(CMV-IgM),巨细胞病毒IgG(CMV-IgG),弓形虫IgM(TOX-IgM)和弓形虫IgG(TOXIgG),并对检测结果进行统计分析,比较各指标和不同人群之间阳性率的差异性。结果 4056例孕前妇女血清中RV-IgG,CMV-IgM,CMV-IgG,TOX-IgM和TOX-IgG阳性率分别为78.30%(3176/4056),0.49%(20/4056),73.15%(2967/4056),1.53%(62/4056)和6.19%(251/4056),其中RV-IgG和CMV-IgG阳性率最高。城镇孕前妇女RV-IgG,CMV-IgM,CMV-IgG,TOX-IgM和TOX-IgG阳性率分别为86.67%,0.58%,76.75%,1.97%和10.13%,明显高于乡村孕前妇女,两者结果之间差异有统计意义(χ~2=3.041~14.823,P<0.01~0.05)。养宠物的孕前妇女血清中RV-IgG,CMV-IgM,CMV-IgG,TOX-IgM和TOXIgG阳性率分别为91.23%(836/916),0.55%(5/916),85.15%(780/916),2.51%(23/916)和7.86%(72/916),明显高于非养宠物的孕前妇女,差异有统计学意义(χ~2=3.754~10.917,P<0.01~0.05)。结论深圳宝安区孕前妇女TORCH有一定的感染率,城镇孕前妇女TORCH阳性率明显高于乡村,养宠物孕前妇女高于非养宠物孕前妇女。因此,应加强对孕前妇女对宠物养殖管理宣传教育,建议孕前妇女尽量减少接触宠物,并孕前进行TORCH筛查,减少甚至杜绝孕前TORCH感染。Objective：To understand the infection status of shenzhen baoan district from 2016 to 2017 in 18~35 pregnant women TORCH,and analyze the risk factors of infection,explore its popular distribution characteristics,provide the basis for further diagnosis and prevention of the TORCH infection. Methods：Randomly collected from February 2016 to August 2017 in our hospital for pregnancy eugenic screening 18~35 pregnant women in 4056 cases,among which 2232 were town,village 1824 cases,respectively,using enzyme-linked immunoassay（ELISA）to detect the serum of rubella virus IgG（RV-IgG）,cytomegalovirus IgM（CMV-IgM）,cytomegalovirus IgG（CMV-IgG）,toxoplasma IgM（TOX-IgM）and toxoplasma IgG（TOX-IgG）,and the detection results were statistically analyzed and compared of the difference of positive rate between each index and different populations. Results：RV-in 4056 cases of pregnant women serum IgG,CMV-IgM,CMV-IgG,TOXIgM and TOX-IgG positive rate was 78.30%（3176/4056）,0.49%（20/4056）,73.15%（2967/4056）,1.53%（62/4056）and 6.19%（251/4056）,including the RV-IgG and CMV-IgG positive rate is highest. Urban pregnant women RV-IgG,CMVIgM,CMV-IgG,TOX-IgM and TOX-IgG positive rate were 86.67%,0.58%,76.75%,1.97% and 10.13%,significantly higher than the rural pregnant women,the difference had statistical significance between two results（chi-square = 3.041~14.823,P〈0.01~0.05）. Pet RV-IgG in serum of pregnant women,CMV-IgM,CMV-IgG,TOX-IgM and TOX-IgG positive rate was 91.23%（836/916）,0.55%（5/916）,85.15%（780/916）,2.51%（23/916）and 7.86%（72/916）,significantly higher than that of non pregnant women have a pet,difference was statistically significant（chi-square = 3.754~10.917,P〈0.01~0.05）. Conclusion：There is a certain infection rate in the women′s TORCH in Baoan district,Shenzhen. The positive rate of female TORCH in the towns and cities is significantly higher than that in the countryside,and the pre-pregnant women are higher than those in the pre-pregnancy. Therefore,ed

关 键 词：孕前妇女 TORCH感染 感染现状 危险因素 调查分析 

分 类 号：R714.25[医药卫生—妇产科学]