对镇江市MSM开展以梅毒筛查和转介为主的综合干预的研究  

HIV/STDs intervention among MSM based on screening and referral

作　　者：刘晓霞[1] 张明辉[1] 叶鲁 李张[1] 成奕[1] 刘超[1] 阮芸[1] 胡成锋 傅更锋 梁国钧[3] 郑志菊[3] 王千秋[3] LIU Xiaoxia1 , ZHANG Minghui1, YE Lu1, LI Zhang1 , CHENG Yi1 , LIU Chao1 , RUAN Yun1 , HU Chengfeng1 , FU Gengfeng2, LIANG Guojun3, ZHENG Zhiju3, WANG Qianqiu3(1. Zhenjiang Municipal Center for Disease Control and Prevention, Zhenjiang 212003, China; 2. Jiangsu Provincial Center for Disease Control and Prevention; 3. Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College ; National Center for Sexually Transmitted Disease Control, China Center for Disease Control and Preventio)

机构地区：[1]镇江市疾病预防控制中心,江苏镇江212003 [2]江苏省疾病预防控制中心,南京210009 [3]中国疾病预防控制中心性病控制中心,南京210024

出　　处：《中国艾滋病性病》2018年第3期283-285,301,共4页Chinese Journal of Aids & STD

摘　　要：目的探索梅毒筛查和转介在男男性行为者（MSM）综合干预中的作用。方法 2013-2015年期间,应用滚雪球方法招募MSM作为研究对象,开展问卷调查,并进行梅毒检测,为梅毒筛查阳性者提供转介服务及随访。结果调查的1 345例MSM,年龄中位数及四分位间距（IQR）为27.0岁（23.0~35.0）,学历以高中及以上为主,占86.5%（1 164例）。HIV阳性率为6.8%（91例）,梅毒血清学阳性率18.1%（244例）,梅毒感染率9.2%（124例）。对梅毒血清学阳性者转介成功率73.4%（179/244）,转介治疗一年后随访显示,转介到定点医院梅毒治愈率为87.2%（34/39）,高于非定点医院的54.5%（12/22）,调查对象转介后梅毒知识知晓率为91.0%（131/144）、最近一次安全套使用率为72.2%（104/144）,最近一个月坚持使用安全套的比例为50.0%（72/144）,均高于转介前,差异有统计学意义（P〈0.05）。结论通过开展综合干预,能提高MSM梅毒防治知识的知晓率和保护意识,减少该人群中艾滋病性病传播的危险因素。Objective To explore effectiveness of the intervention by syphilis screening and referral among MSM.Methods From 2013 to 20 l5,the snowball sampling method was used to recruit MSM for investigation by self-designed questionnaires.Blood samples were collected for serological analysis of HIV and syphilis.Clinic Attendants with positive syphilis serology received referral and follow-up services.Results A total of 1345 MSM were surveyed.The median age was 27.0（IQR：23.0-35.0）;86.5%（1164/1345）got education of high school or above.6.8%（91/1345）were infected with HIV.The morbidity of syphilis was 18.1%（244/1345）while the current syphilis infection rate was 9.2%（124/1345）.73.4%（179/244）of the cases with positive syphilis serology were referred to the designated hospital.After one year of treatment in the designated hospital,the negative conversion rate of syphilis,condom use and knowledge of syphilis were higher,and the difference was significant compared to those treated in the non-designated hospital.Conclusion The intervention based on syphilis screening and referral among MSM is feasible and can increase the awareness of HIV/STDs knowledge and self-protection as well as condom use and HIV testing.

关 键 词：梅毒 男男性行为者 筛查转介治疗 

分 类 号：R759[医药卫生—皮肤病学与性病学]