右美托咪定复合丙泊酚在清醒气管插管中的麻醉效果及对呼吸和循环的影响  

Anesthesia Effect of Dexmedetomidine Combined with Propofol on Clear Tracheal Intubation and Influences on Respiration and Circulation

作　　者：王继爱[1] 丁宝纯[1] 刘海晶 董萍[1] 王福旭 肇丽梅[2] WANG Ji-ai1, DING Bao-chun1, LIU Hai-jin1, DONG Ping1, WANG Fu-xu1, ZHAO Li-mei2(1 Department of Anesthesiology, Huludao Central Hospital, Huludao, Liaoning, 125001, China; 2 Department of Anesthesiology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, 110004, Chin)

机构地区：[1]葫芦岛市中心医院麻醉科,辽宁葫芦岛125001 [2]中国医科大学附属盛京医院麻醉科,辽宁沈阳110004

出　　处：《现代生物医学进展》2018年第3期485-488,共4页Progress in Modern Biomedicine

基　　金：辽宁省自然科学基金项目(30300327)

摘　　要：目的:探讨右美托咪定复合丙泊酚应用于清醒气管插管的麻醉效果及对呼吸和循环的影响。方法:选择我院2015年1月~2016年12行清醒气管插管患者80例,按麻醉方式分组,每组40例,对照组采用丙泊酚麻醉诱导,研究组麻醉诱导予以右美托咪定复合丙泊酚。比较两组麻醉效果、呼吸和循环的变化及并发症的发生情况。结果:研究组插管时间、Ramsay评分、耐受良好、插管成功率、呼吸次数、分钟通气量、心率、平均动脉压均显著高于对照组(P<0.05),潮气量、去甲肾上腺素、皮质醇、并发症总发生率均明显低于对照组(P<0.05)。结论:右美托咪定复合丙泊酚用于清醒气管插管的麻醉效果确切,可使有效减轻对呼吸和循环的影响。Objective： To research the anesthesia effect of dexmedetomidine combined with propofol on the clear tracheal intubation and the influences on the respiration and circulation. Methods： 80 cases of clearly tracheal intubation from January 2015 to 2016 were selected and divided into two groups according to different anesthesia with 40 patients in each group. The control group was induced by propofol anesthesia, the research group was induced by dexmedetomidine combined with propofol anesthesia. The anesthetic effect, breathing and circulation, and incidence of complications were compared between the two groups. Results： The intubation time,ramsay score, well tolerated, intubation success rate, respiratory rate, minute ventilation, heart rate and mean arterial pressure of research group were significantly higher than those of the control group（P〈0.05）, the tidal volume, serum norepinephrine and cortisol levels of research group were lower than those of the control group（P〈0.05）. Conclusion： Dexmedetomidine combined with propofol was effective in the awake tracheal intubation, which could reduce the inhibition of respiration and circulation.

关 键 词：清醒气管插管 右美托咪定 丙泊酚 复合麻醉 呼吸循环 

分 类 号：R614[医药卫生—麻醉学]