Partner switching for Ran during the mitosis dance  

作　　者：Yang Yang Hongtao Yu 

机构地区：[1]Howard Hughes Medical Institute, Department of Pharmacology, University of Texas Southwestem Medical Center, Dallas, TX 75390, USA

出　　处：《Journal of Molecular Cell Biology》2018年第1期89-90,共2页分子细胞生物学报（英文版）

摘　　要：Mitosis is one of the most fascinating pro- cesses in biology, and is often described as a well-choreographed dance. During mitosis, sister chromatids attach to dynamic microtubules in the mitotic spindle, align and oscillate at the metaphase plate, separ- ate synchronously at the metaphase-ana- phase transition, and are partitioned equally into the two daughter cells. Chromosome missegregation leads to aneuploidy and genomic instability, which can drive tumori- genesis under certain contexts.

关 键 词：有丝分裂期 跳舞 切换 姐妹染色单体 职业人员 阶段转变 不稳定性 生物学 

分 类 号：Q754[生物学—分子生物学] S513[农业科学—作物学]