地枫皮氯仿部位的化学成分研究  

Research on Chemical Constituents of Chloroform Extract from Illicii Cortex

作　　者：宁德生[1] 符毓夏 程玲 谢运昌[1] 潘争红[1] NING De-sheng1 , FU Yu-xia1 , CHENG Ling2, XIE Yun-chang1 , PAN Zheng-hong1(1. Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Chinese Academy of Sciences, Guilin 541006, China ; 2. School of Chemical Science and Technology, Yunnan University, Kunming 650031, Chin)

机构地区：[1]广西壮族自治区中国科学院广西植物研究所/广西植物功能物质研究与利用重点实验室,广西桂林541006 [2]云南大学化学科学与工程学院,云南昆明650031

出　　处：《中药材》2017年第9期2093-2097,共5页Journal of Chinese Medicinal Materials

基　　金：广西科技开发项目(桂科合14125008-2-23);广西植物功能物质研究与利用重点实验室自主研究课题(ZRJJ2014-2;ZRJJ2016-16)

摘　　要：目的:研究地枫皮氯仿部位的化学成分。方法:将传统分离方法与现代色谱分离技术相结合分离纯化化合物,经波谱数据分析和文献比对鉴定化合物结构。结果:从地枫皮的氯仿提取物中分离得到14个化合物,分别鉴定为:tashironin(1)、tashironin A(2)、14-O-benzoylfloridanolide(3)、magnolol(4)、dehydrodieugenol(5)、isodunnianol(6)、difengpin(7)、dihydrocubebin(8)、sakuraresinol(9)、rel-(2α,3β)-7-O-methylcedrusin(10)、2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-propane-1,3-diol(11)、bursephenylpropane(12)、3,3'-dimethoxy-4,8'-oxyneoligna-9,4',7',9'-tetraol(13)、(7R,8R)-4-O-(glycer-2-yl)-7,9,9'-trihydroxy-3,5,3'-trimethoxy-8-O-4'-neolignan(14)。结论:其中,化合物1、3、6、8、12为首次从该植物中分离得到。Objective： To study the chemical constituents of chloroform of Illicii Cortex. Methods： The compounds were isolated and purified by combining conventional separation methods and modern chromatographic separation technology,and their chemical structures were elucidated by spectral data analysis and comparing with the previous literatures. Results： 14 compounds were obtained from chloroform extract of Illicii Cortex and their structures were identified as tashironin（ 1）,tashironin A（ 2）,14-O-benzoylfloridanolide（ 3）,magnolol（ 4）,dehydrodieugenol（ 5）,isodunnianol（ 6）,difengpin（ 7）,dihydrocubebin（ 8）,sakuraresinol（ 9）,rel-（ 2α,3β）-7-O-methylcedrusin（ 10）,2-[4-（ 3-hydroxypropyl）-2-methoxyphenoxy]-propane-1,3-diol（ 11）,bursephenylpropane（ 12）,3,3＇-dimethoxy-4,8＇-oxyneoligna-9,4＇,7＇,9＇-tetraol（ 13） and（ 7 R,8 R）-4-O-（ glycer-2-yl）-7,9,9＇-trihydroxy-3,5,3＇-trimethoxy-8-O-4＇-neolignan（ 14）. Conclusion： Compounds 1,3,6,8 and 12 are separated from this plant for the first times.

关 键 词：地枫皮 化学成分 结构鉴定 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]