近40年血脂异常中医证候动态演变规律的研究  

Study on the changing law of traditional Chinese medicine syndromes of dyslipidemia in recent 40 years

作　　者：尹湘君 何庆勇[1] 王阶[1] 李军[1] YIN Xiang-jun;HE Qing-yong;WANG Jie;LI Jun(Guang＇anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China;Beijing University of Chinese Medicine, Beijing 100029, China)

机构地区：[1]中国中医科学院广安门医院,北京100053 [2]北京中医药大学,北京100029

出　　处：《中华中医药杂志》2018年第4期1523-1526,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金项目(No.81202803);中央公益性科研院所基本科研业务费专项资金资助项目(No.ZZ0908023)~~

摘　　要：目的:探析血脂异常中医证候、证候要素、证候要素靶位的分布及其动态演变规律。方法:检索1975年1月-2015年12月CNKI发表文献,对文献中关于血脂异常中医证候、证候要素、证候要素靶位数据进行统计分析。结果:共纳入文献93篇,总病例数23 270例,血脂异常常见证候有痰浊阻滞(21.75%)、气滞血瘀(12.67%)、阴虚阳亢(11.74%)等,常见证候要素有痰浊(30.40%)、阴虚(26.06%)、血瘀(25.35%)等,相关证候要素靶位有脾(58.69%)、肾(42.87%)、肝(37.87%)等。随着时间的推移,血脂异常患者虚证逐渐减少,而实证逐渐增多;证候要素血瘀在近40年动态演变过程中所占百分比波动不大;血脂异常患者主要证候要素靶位由肝、肾转向脾。结论:血脂异常实证逐渐增多,近10年证候以痰浊阻滞、气滞血瘀为主,证候要素以痰浊、血瘀为主,证候要素靶位以脾为多;虚证逐渐减少,近10年以气虚为主。Objective： To reveal the distribution and changing law of TCM syndromes, syndrome factors and affecting targets of dyslipidemia. Methods： Searching the published literature on CNKI from January 1975 to December 2015 to analyze the distribution and changing law of TCM syndromes, syndrome factors and affecting targets of dyslipidemia. Results： Nintythree literatures and 23 270 cases were included, the common syndromes of dyslipidemia were phlegm stasis （21.75%）, qi stagnation and blood stasis （12.67%）, yin deficiency and yang exuberant （11.74%）, etc; the common syndrome factors were phlegm turbid （30.40%）, yin deficiency （26,06%）, blood stasis （25.35%）, etc; the common affecting targets were spleen （58.69%）, kidney （42.87%）, liver （37.87%）, etc, Over time, deficient patterns were decreasing, while empirical patterns were gradually increasing, syndrome of blood stasis fluxs small in recent 40 years; the main affecting targets transform from liver and kidney to spleen. Conclusion： Empirical patterns of dyslipidemia are gradually increasing, syndromes of phlegm stasis, blood stasis and qi stagnation are preferred; syndrome factors of phlegm turbid, blood stasis are preferred; affecting target of spleen is preferred; while the deficient patterns are gradually decreasing, syndrome factor of qi deficiency is preferred in recent 10 years.

关 键 词：血脂异常 证候 证候要素 证候要素靶位 文献 

分 类 号：R259[医药卫生—中西医结合]