基于“脾-线粒体”相关理论谈痰瘀互结所致动脉粥样硬化的微观变化  

Microscopic Changes of AS Caused by Phlegm and Blood Stasis Due to Theory of Spleen-Mitochondria

作　　者：陈宁[1] 宋囡[1] 贾连群[1] 吕美君[1] 杨关林[1] CHEN Ning;SONG Nan;JIA Lianqun;LYU Meijun;YANG Guanlin(Key Laboratory of Ministry of Education for TCM Viscera - State Theory and Applications of Liaoning University of Traditional Chinese Medicine, Translational Medicine Research Center of traditional Chinese Medicine In Liaoning , Liaoning University of Traditional Chinese Medicine, Shenyang 110847, Liaoning, China)

机构地区：[1]辽宁中医药大学中医脏象理论及应用教育部重点实验室辽宁省中医转化医学研究中心

出　　处：《中华中医药学刊》2018年第4期849-851,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家重点基础研究发展计划(“973”计划)项目(2013CB531704);辽宁省自然科学基金项目(2015020394);辽宁省高等学校优秀人才支持计划项目(LR2015041);辽宁省教育厅一般项目(L201613)

摘　　要：近年来多数学者将线粒体作为靶点来研究其与动脉粥样硬化之间的联系机制与治疗。而线粒体作为人体细胞的＂能量加工厂＂与中医中＂脾＂的作用有着异曲同工之妙,脾作为后天之本,气血生化之源,也为人体提供必要的营养基础,并且脾失健运所产生的痰浊血瘀亦是动脉粥样硬化形成的关键,从＂脾-线粒体＂之间的关联来探究脾虚痰瘀在动脉粥样硬化形成过程中的科学内涵。In recent years,many scholars have studied the formation mechanism and treatment of atherosclerosis from the perspective of mitochondria. At the same time,the mitochondria,as the ＂power plant＂of the human body,is very similar to the＂spleen＂of TCM. The＂spleen＂is the foundation which can generate Qi and blood to provide the necessary material basis for the human body. The phlegm turbidity and blood stasis caused by dysfunction of spleen in transportation is the key to the formation of atherosclerosis. The author wants to explore the scientific connotation of the phlegm and blood stasis caused by the deficiency of the spleen in the process of atherosclerosis formation from the relationship between the spleen and the mitochondria.

关 键 词：痰浊血瘀 动脉粥样硬化 线粒体 

分 类 号：R543.3[医药卫生—心血管疾病]