密闭式双联血液透析用体外循环管路在血液透析联合血液灌流治疗中的应用  

Application of closed double cardiopulmonary bypass in hemodialysis combined with hemoperfusion

作　　者：龙玲玲[1] 马志芳[1] 王沙沙[1] 任琴琴[1] 李银霞 LONG Lingling,MA Zhifang,WANG Shasha,REN Qinqin, LI Yinxia(Blood Purification Center, Department ol Nephrology, General Hospital of PLA , Beijing 100853, Chin)

机构地区：[1]解放军总医院肾科血液静化中心,北京100853

出　　处：《转化医学杂志》2018年第2期90-92,共3页Translational Medicine Journal

摘　　要：目的探讨密闭式双联血液透析用体外循环管路在血液透析联合血液灌流治疗中的应用。方法选择解放军总医院2014年1月至2015年12月维持性血液透析患者60例,进行血液透析联合血液灌流治疗,随机分为对照组和试验组各30例,每例均行10次治疗,对照组采用常规的单根直管管路连接血液透析器与血液灌流器,试验组采用密闭式双联血液透析用体外循环管路连接血液透析器与血液灌流器。对比分析管路预冲、结束治疗的操作时间、管路凝血、管口暴露、血液滴洒等指标。结果与对照组比较,试验组管路预冲、结束治疗的操作时间、血液灌流器及透析器凝血发生率等明显较少,管口暴露及血液滴洒等发生明显较低,差异有统计学意义(P<0.05)。结论采用密闭式双联血液透析用体外循环管路进行血液透析联合血液灌流治疗优于常规管路,值得临床推广。ObjectiveTo investigate the clinical application of closedcircuit extracorporeal circuit for hemodialysis in hemodialysis combined with hemoperfusion. MethodsSixty patients with maintenance hemodialysis from January 2014 to December 2015 were enrolled in this study. Hemodialysis and blood perfusion were randomly divided into control group and experimental group （n=30）. Each patient underwent 10 rounds of treatment. In the control group, the conventional single straight tube was used to connect hemodialyzer and blood perfusion device. In the experimental group, the closed dialysis hemodialysis cardiopulmonary bypass was used to connect hemodialyzer and blood perfusion device. Conduct pipeline preflushing, the end of the treatment of the operation time, coagulation of the pipeline, nozzle exposure, such as blood drip were analyzed. ResultsIn the experimental group, the operation time of the preflushing of the pipeline, the end of treatment, the incidence of blood perfusion of the blood perfusion device and the dialyzer were obviously less than those in control group. The incidence of orifice exposure and blood dripping were significantly lower than that of the control group （P〈0.05）. ConclusionThe closed double dialysis hemodialysis with extracorporeal circulation pipeline for hemodialysis combined with blood perfusion is superior to conventional pipeline, which is worth of clinical application.

关 键 词：血液透析用体外循环管路 血液透析 血液灌流 

分 类 号：R459.5[医药卫生—治疗学]