核酸适配体生物传感器在农残检测中的研究进展  

Research progresses of DNA aptosensors for pesticide detection

作　　者：李凤球 潘宏程[1,2,3] 袁亚利 LI Feng-qiu1, PAN Hong-cheng1,2,3 and YUAN Ya-li1,2,3(1. College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004; 2. Guangxi Key Laboratory of Electrochemical and Magneto-chemical Function Materials, Guilin 541004; 3. Guangxi Colleges and Universities Key Laboratory of Food Safety and Detection, Guilin 54100)

机构地区：[1]桂林理工大学化学与生物工程学院,桂林541004 [2]广西电磁化学功能物质重点实验室,桂林541004 [3]广西高校食品安全检测重点实验室,桂林541004

出　　处：《分析试验室》2018年第4期488-496,共9页Chinese Journal of Analysis Laboratory

基　　金：广西电磁功能物质重点实验室研究基金(EMFM20161202)资助

摘　　要：由于核酸适配体具有特异性强、亲和力高、制备方便、易修饰、稳定性好、目标物多样性等特点,基于适配体的传感器研究工作一直是广大科研工作者的研究热点。相较于具有特异性识别的生物酶的使用,核酸适配体在农药残留检测中的应用正在发展中,具有广阔的前景。本文主要介绍近两年来核酸适配体生物传感器在农药分子检测领域的相关进展。Aptamers have the advantages of admirable specificity, high binding affinity, facile preparation,ease to be modified,high stability,diversity of targets and so on. As a result,sensor studies based on aptamers have always been the majority focus of analytical researchers. During recent years,the safety problems in the environmental and food safety fields caused by pesticide residues raised the close attention of the whole society,and variety of recognition and detection strategies for different categories of pesticide have emerged accordingly. Compared with the application of bioenzyme,usage of aptamers as recognition element of pesticide are still in development. Herein,recent progresses of DNA aptamer biosensors in the field of pesticide residual detection were discussed.

关 键 词：核酸适配体 生物传感器 农药残留 

分 类 号：TQ45[化学工程—农药化工] O657.1[理学—分析化学]