密集颅部电针刺激治疗和针刺治疗对抑郁症患者再入院风险的影响  

Effect of Dense Cranial Electro-acupuncture Stimulation and Acupuncture on the Risks of Readmission for Major Depressive Disorder Patients

作　　者：伍远菲[1] 吴升伟[1] 廖雪珍 徐琰[1] 刘赟[1] 朱志敏 禤正正 杨铭哲[1] WU Yuanfei1, WU Shengwei1, LIAO Xuezhen1, XU Yah1, LIU Yun1, ZHU Zhimin1, XUAN Zhengzheng2, YANG Minzhe1(1.Affiliated Hospital of Guangzhou Medical University, Guangdong Guangzhou 510370, China ;2. Traditional Chinese Medicine Hospital of Guangzhou Province, Guangdong Guangzhou 510120, Chin)

机构地区：[1]广州医科大学附属脑科医院(广州市惠爱医院),广东广州510370 [2]广东省中医院,广东广州510120

出　　处：《中医药临床杂志》2018年第3期497-501,共5页Clinical Journal of Traditional Chinese Medicine

基　　金：广州市医药卫生科技项目(编号:20152A011015)

摘　　要：目的:探讨影响抑郁症患者再入院风险的相关因素及密集颅部电针刺激治疗和针刺治疗对抑郁症患者再入院风险的影响。方法:将我院2015年5月至2015年10月收治的85名经住院治疗并自愿参加研究的以SSRI类药物为基础治疗的抑郁症患者随机分为西药组(n=28),西药+电针组(n=29),西药+针刺组(n=28),并对其进行量表评估及随访观察其再入院天数。结果:抑郁症患者出院后一年内的再入院率为36.47%。Cox回归模型生存分析显示,患者的受教育年限(HR=0.82,P=0.006)、出院自知力评估(HR=0.85,P<0.001)、出院药物副反应评估(HR=1.16,P<0.001)、住院付费方式(HR=0.29,P=0.007)、家属婚姻状况(HR=0.09,P=0.004)、是否和家属住一起(HR=0.45,P=0.035)是影响患者再入院的有关因素。逐步回归分析结果提示,西药+针刺组的再入院风险只有西药组的0.19(95%CI=0.07-0.53,P=0.001),而西药+电针组的再入院风险只有西药组的0.13(95%CI=0.04-0.40,P<0.001)。结论:以SSRI类药物治疗为主的抑郁症患者联合密集颅部电针刺激治疗或针刺治疗可降低患者的再入院风险。Objective： To explore the factors that influence the risk of rehospitalization in patients with depression and the effect of intensive cranial electro-acupuncture stimulation and acupuncture treatment on the rehospitalization risk of patients with depression. Methods： Thirty-five patients with depressive disorder who were hospitalized and vol- unteered to participate in the study from May 2015 to October 2015 in our hospital were randomly divided into West- ern medicine group （n=28） and western medicine＋Electro-acupuncture group （n=29）, western medicine＋acupuncture group （n=28）, and its assessment of the scale and follow-up observation of the number of re-admission days. Results： The re-admission rate of depression patients within one year after discharge was 36.47%. Cox regression model sur- vival analysis showed that the patient＇ s education years （HR=0.82, P=0.006）, discharge insight （HR=0.85, P〈0.001）, discharge drug side-effects assessment （HR=I.16, P〈0.001 ）, Inpatient payment methods （HR=0.29, P=0.007）, fam- ily members＇ marital status （HR=0.09, P=0.004）, and whether they lived with family members （HR=0.45, P=0.035） were factors that affected the patient＇ s readmission. Results： The re-admission rate of depression patients within one year after discharge was 36.47%. Cox regression model survival analysis showed that the patient＇ s education years （HR=0.82, P=0.006）, discharge insight （HR=0.85, P〈0.001）, discharge drug side-effects assessment （HR=1.16,P〈0.001 ）, Inpatient payment methods （HR=0.29, P=0.007）, family members＇ marital status （HR=0.09, P=0.004）, and whether they lived with family members （HR=0.45, P=0.035） were factors that affected the patient＇ s readmission. Stepwise regression analysis suggested that the re-admission risk of Western medicine＋acupuncture group was only 0.19 （95% CI=0.07-0.53, P=0.001） in Western medicine group, while the re-admission risk of western medicine＋electro- acupuncture

关 键 词：抑郁症 再入院风险 密集颅部电针刺激治疗 针刺治疗 

分 类 号：R259[医药卫生—中西医结合]