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作 者:马莉[1] MA Li(Department of Obstertries and Gynecology, Shanghai Jiaotong University Affiliated the Sixth People's Hospital, Shanghai 200233, Chin)
机构地区:[1]上海交通大学附属第六人民医院妇产科,上海200233
出 处:《世界临床药物》2018年第3期153-156,共4页World Clinical Drug
摘 要:早发性卵巢功能不全(POI)是指育龄期女性出现的以月经紊乱、伴体内高促性腺激素和低雌激素水平为特征的一种疾病。激素补充治疗是POI的主要治疗方法,可缓解患者低雌激素水平引起的临床症状,提高生活质量;免疫治疗有助于恢复某些免疫性疾病导致的POI患者的卵巢功能和生育能力;中医治疗POI具有很大的发展潜力;新兴的辅助生殖技术、卵巢冷冻移植技术为有生育要求的POI患者提供了新的治疗途径。本文综述POI的临床治疗新进展。Premature ovarian insufficiency(POI) is characterized with menstrual disorder, such as hyperprolanemia and hypoestrogenism in reproductive-aged women. The hormone replacement therapy is main treatment for relieving clinical symptoms caused by low estrogen level, which can improve the quality of life. Usually, the immunotherapy can restore the ovary function and fertility of the POI patients caused by some immune diseases. Chinese medicine is also proved to be a potent effective management. Recently, the new therapies, such as assisted reproductive technology, oocyte and ovarian tissue cryopreservation and transplantation, provide some options for POI patients, who want fertility. This review describes the progress of clinical treatment for POI.
关 键 词:早发性卵巢功能不全(POI) 辅助生殖技术 治疗
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