夏科氏足的病理生理和诊疗新进展  

Pathophysiology and the progress of treatment of Charcot foot

作　　者：王志伟[1] 吴学建[1] 朱旭[1] 吴晗[1] 孟祥雷[1] Wang Zhiwei, Wu Xuejian, ZhuXu, Wu Han, Meng Xianglei(Department of Orthopaedics, the First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Chin)

机构地区：[1]郑州大学第一附属医院骨科,450052

出　　处：《中国实用医刊》2018年第3期123-126,共4页Chinese Journal of Practical Medicine

摘　　要：夏科氏足是足踝部进展性的、非传染性的、炎症破坏性的病理过程，传统认为其是三期梅毒的一种后遗症，脊髓空洞症、麻风病、帕金森病、风湿性疾病等也可继发该病，大多数继发于糖尿病。近年来，随着糖尿病患者的逐年增多及生命周期的延长，夏科氏足患者亦逐渐增多，对社会产生了严重的负面影响。本文总结了夏科氏足的病理生理学、诊断分级的研究成果，并就最新的循证医学证据对夏科氏足的非手术治疗及手术治疗方式展开论述。Objective Charcot foot is a progressive, noninfectious, destructively inflammatory pathological process of the foot and ankle, and is considered as a sequela of tertiary syphilis traditionally. Syringomyelia, leprosy, Parkinson disease, rheumatoid disease can also lead to this disease, however, in the vast majority of current patients it is secondary to diabetes. As the prevalence of diabetes increasing and lives of these patients prolonging, population of patients with Charcot foot increases gradually, and Charcot foot arthropathy creates a severe negative impact on patients and society. This lecture review aims at summarizing current understanding of Charcot foot with focusing on the pathophysiology, diagnosis, classifications, and providing an analysis of the latest evidence for conservative treatment strategies and evidence-based options for operative intervention.

关 键 词：夏科氏足 踝 神经性关节炎 保守治疗 手术治疗 

分 类 号：R681[医药卫生—骨科学]