持续或间断氧气雾化吸入在中重度颅脑损伤气道黏膜干燥患者中的应用评价  

作　　者：张满萍[1] 石红荣[1] 丁菊妃[1] 王晓珊 陈智英[1] 

机构地区：[1]浙江省新昌县人民医院急诊科,312500

出　　处：《浙江临床医学》2018年第4期704-705,共2页Zhejiang Clinical Medical Journal

摘　　要：目的评价持续或间断氧气雾化吸入在中重度颅脑损伤气道黏膜干燥患者中的应用效果。方法纳入2015年1月＆2017年6月外科ICU与神经外科的非气管插管与气管切开的中重度颅脑损伤140例患者，随机分为观察组和对照组，分别采取持续或间断氧气雾化吸入和普通鼻塞法吸氧。比较两组的痰痂形成、气道黏膜出血、刺激性咳嗽、肺部感染的发生率，以及痰液粘稠度、住院时间和医疗费用。结果观察组的痰痂形成、气道黏膜出血、刺激性咳嗽以及肺部感染的发生率均明显低于对照组，痰液粘稠度明显好于对照组，住院时间明显短于对照组，医疗费用明显少于对照组，差异均具有统计学意义（P〈0．05）。结论与普通鼻塞法吸氧比较，持续或间断氧气雾化吸入能明显改善中重度颅脑损伤气道黏膜干燥患者的痰液粘稠度，降低并发症发生率，缩短住院时间和降低医疗费用。Objective To evaluate sustained or intermittent oxygen aerosol inhalation in the treatment of moderate and severe traumatic brain injury in patients with airway mucosa. Methods 140 cases of moderate and severe traumatic brain injury underwent neurosurgery non-tracheal intubation and tracheostomy included in surgical ICU from January 2015 to June 2017 were randomly divided into observation group and control group, the continuous or intermittent oxygen mist Inhalation and general nasal occlusion oxygen were taken respectively. Phlegm scab formation, airway mucosal bleeding, irritating cough, incidence of pulmonary infection, sputum viscosity, length of hospital stay, and medical expenses were compared between the two groups. Results The sputum scab formation, airway mucosal hemorrhage, irritating cough and lung infection in the observation group were significantly lower than those in the control group, the sputum viscosities were significantly better than those in the control group, the hospitalization time was significantly shorter than that in the control group, and the medical cost was significantly less than the control group, the difference was statistically significant （P〈0.05） . Conclusion Compared with ordinary nasal occlusion oxygen, continuous or intermittent oxygen atomization inhalation can significantly improve the moderate and severe traumatic brain injury in patients with mucus membrane sputum viscosity, reduce the incidence of complications, reduce hospital stay and reduce medical costs.

关 键 词：氧气雾化吸入 中重度颅脑损伤 气道湿化 肺部感染 

分 类 号：R651.15[医药卫生—外科学]