不同运动强度对肾上腺原癌基因C-fos蛋白表达的作用  

Effects of different exercise intensities on the expression of adrenal gland C-fos protein in rats

作　　者：郭林[1] 曹建民[2] 田敏[3] 徐晓阳[4] 王琳[2] 周铁民[2] 

机构地区：[1]山东师范大学体育学院,山东济南250014 [2]北京体育大学,北京100084 [3]山东体育学院,山东济南250014 [4]华南师范大学体育科学学院,广东广州510631

出　　处：《体育学刊》2002年第3期33-34,37,共3页Journal of Physical Education

摘　　要：通过观察在 3种不同运动强度下 ,大鼠肾上腺原癌基因C -fos蛋白表达的变化、尿总蛋白 (TP)排泄率的变化和相互关系 ,研究运动强度对肾上腺C -fos蛋白表达的影响 ,以及C -fos蛋白表达的变化在运动性疲劳、恢复及机能评定中的意义。结果表明 ,运动强度越大 ,肾上腺C -fos蛋白表达增加也大 ,且运动后恢复期恢复时间越长 ,肾上腺C -fos蛋白表达量越大。研究中第 4次C -fos表达测定都比第一次测定显著升高 (P <0 .0 5 )。在尿TP排泄率早已恢复的情况下 ,代表肾上腺结构、机能状态的C -fos表达却持续升高 ,表明利用肾上腺C -fos蛋白表达来进行运动性疲劳、恢复的判断及机能评定时 ,应注意肾上腺C -fos蛋白表达的时间特性。This research was designed to observe the changes of expression of adrenal gland C-fos protein, excretion rate of urinary TP and its relation, and to study the influence of exercise intensity on the expression of adrenal gland C-fos protein, as well as the significance in the judgment of sports fatigue, recovery and function evaluation. The results indicated that the higher exercise intensity and longer recovery period after exercise, the higher increase in the expression of adrenal gland C-fos. The expression increased more significantly at the 4th test than it at 1st test among the three groups ( P<0.05). On the condition of the recovery of urinary TP excretion rate, the C-fos which representing the structure and function of adrenal gland still increased. It indicated attention must be paid to the time profile of the C-fos expression when the expression of adrenal gland C-fos was used to judge sports fatigue, recovery and function evaluation.

关 键 词：肾上腺 C-FOS蛋白 尿TP 运动强度 

分 类 号：G804.7[文化科学—运动人体科学]