秦皇岛市2013—2015年新报告HIV/AIDS病例首次CD4^+T淋巴细胞检测结果  

Results of first CD4^+T lymphocyte tests of newly detected HIV/AIDS cases in Qinhuangdao,2013-2015

作　　者：张静[1] 冯艳洁[1] 刘毅 郭香萍 ZHANG Jing;FENG Yanjie;LIU Yi;GUO Xiangping(Qinhuangdao Center for Disease Control and Prevention, Qinhuangdao, Hebei 066000, Chin)

机构地区：[1]秦皇岛市疾病预防控制中心,河北秦皇岛066000

出　　处：《中国热带医学》2018年第4期399-401,共3页China Tropical Medicine

摘　　要：目的了解2013—2015年秦皇岛市新报告的艾滋病病毒(HIV)感染者/艾滋病(AIDS)病例的首次CD4^+T淋巴细胞水平及其影响因素,为开展抗病毒治疗提供依据。方法采用流式细胞仪对新报告的HIV/AIDS病例进行首次CD4^+T淋巴细胞绝对值计数检测,对相关数据进行统计分析。结果 112例患者中,CD4^+T淋巴细胞计数最小值为4个/μL,最大值为972个/μL,均数为(365.4±196.0)个/μL。其中≤200个/μL 21例(18.75%);201~350个/μL 40例(35.71%);351~500个/μL 27例(24.11%);>500个/μL 24例(21.43%)。不同性别、年龄患者的CD4^+T淋巴细胞检测结果差异有统计学意义(P<0.05)。不同年份、婚姻状况、文化程度、感染途径患者的CD4^+T细胞计数差异均无统计学意义(P>0.05)。结论秦皇岛市HIV/AIDS病例首次CD4^+T淋巴细胞水平相对偏低,18.8%新发现病例已进入艾滋病期,应加强HIV检测相关知识的宣传和普及,做到早发现,早治疗,提高患者生命质量。ObjectiveTo understand the levels of CD4^＋T lymphocytes of the first tests in newly detected HIV/AIDS cases and influencing factors in Qinhuangdao City from 2013 to 2015, so as to provide the evidence for improving the antiviral treatment. MethodsThe first CD4^＋T lymphocyte tests were performed by flow cytometry in the newly detected HIV/AIDS cases, and the related data was also collected and analyzed. ResultsAmong 112 HIV infected persons, the minimum value of CD4^＋ T lymphocytes was 4 cells/μL, the maximum was 972 cells/μL, and the average value was （365.4 ± 196.0） cells/μL. In these cases, there were 21 persons with ≤200 cells/μL（18.75%）, 40 persons with 201-350 cells/μL （35.71%）, 27 persons with 351-500 cells/μL （24.11%）, and 24 persons with 〉500 cells/μL （21.43%）. There were significant differences between/among the different gender groups and age groups in the CD4^＋T lymphocyte counts （P〈0.05）, but there were no significant differences among the different years, marriage status, education levels and infection routes （P〉0.05）. ConclusionsThe levels of CD4^＋T lymphocytes in the first detection among HIV/AIDS persons are low in Qinhuangdao City, and 18.8% of the newly detected HIV/AIDS people have entered the AIDS period. It is necessary to strengthen the health education of HIV/AIDS prevention and HIV testing knowledge to achieve the early detection and early treatment in order to improve the life quality of the patients.

关 键 词：艾滋病病毒感染者/艾滋病病人 CD4^+T淋巴细胞 检测 

分 类 号：R512.91[医药卫生—内科学]