三味蒺藜散对高血脂大鼠模型调血脂作用的研究  

Study of the Lipid-regulating Effect of Sanwei Jili Powder on Hyperlipidemic Rat Model

作　　者：韩莹[1] 刘霞 王大海 包宏[1] 韩雪莲[1] 赵中华[1] HAN Ying;LIU Xia;WANG Da-hai;BAO Hong;HAN Xue-lian;ZHAO Zhong-Hua(Medical College, Inner Mongolia University for Nationalities, Tongliao 028000, China;Deparlment of Laboratory, Tongliao City Hospital, Tongliao 028000, China)

机构地区：[1]内蒙古民族大学医学院,内蒙古通辽028000 [2]内蒙古通辽市医院检验科,内蒙古通辽028000

出　　处：《内蒙古民族大学学报（自然科学版）》2017年第6期535-537,共3页Journal of Inner Mongolia Minzu University：Natural Sciences

基　　金：内蒙古自然科学基金资助项目(2012MS1171)

摘　　要：目的:观察三味蒺藜散的调血脂作用.方法:通过复制高血脂动物模型(采用脂质代谢紊乱法)的方法,来探讨三味蒺藜散对高脂血症模型大鼠的血脂是否有调节作用.结果:三味蒺藜散在0.9、1.8g/kg体重剂量条件下能调节高脂饲料所导致的动物脂代谢紊乱,控制其血清胆固醇水平的升高,并一定程度地提高其血清高密度脂蛋白水平.结论:三味蒺藜散在实验剂量条件下能较好的调节高血脂动物的血脂,从而达到机体脂代谢的相对平衡.Objective： To observe the blood lipid regulation effects of Sanwei Jili Powder（SJP）. Methods： The lipid-regulating effect of SJP on hyperlipidemic rat model was studied by establishing hyperlipidemic animal model（using lipid metabolism disorder method）. Results： At the dose of 0.9 and 1.8 g/kg body weight,SJP can regulate animal fat metabolic disorder caused by high fat feed,prevent the increase of serum cholesterol levels,and to a certain extent increase the serum high density lipoprotein cholesterol（HDL-C） level. Conlusion： SJP can well regulate the blood lipid of hyperlipidemia at experimental dose,so as to achieve the relative balance of fat metabolism

关 键 词：三味蒺藜散 实验动物 血脂 高血脂模型 

分 类 号：R291.2[医药卫生—民族医学]