山楂叶总黄酮药理作用研究进展  

Advances in studies of pharmacological effects of Hawthorn leaves flavonoids

作　　者：李劲松[1] 徐颖[2] 孙涛[2] LI Jing-song;XU Ying;SUN Tao(The first people＇s Hospital of Guangyuan, Guangyuan 628017, Sichuan;Chengdu University of Traditional Chinese Medicine, Key Laboratory of Standardization for Chinese Herbal Medicine, Ministry of Education, National Key Laboratory Breeding Base of Systematic Research, Development and Utilization of Chinese Medicine Resources, Chengdu 611137, Sichuan)

机构地区：[1]广元市第一人民医院,四川广元628017 [2]成都中医药大学中药材标准化教育部重点实验室中药资源系统研究与开发利用省部共建国家重点实验室培育基地,四川成都611137

出　　处：《中药与临床》2017年第6期64-64,F0003,共2页Pharmacy and Clinics of Chinese Materia Medica

基　　金：四川省科技厅应用基础研究计划项目(编号:2013JY0068);四川省中医药管理局中药基础研究项目(编号:2014F013);四川省中医药管理局中药及相关产品项目(编号:2016Q053);广元市科技局科技支撑计划项目(编号:14KJZCS003);成都中医药大学科技发展基金(编号:030029041);成都中医药大学科技发展基金(编号:030029053)

摘　　要：山楂叶总黄酮为山楂叶的主要活性物质群,国内外研究发现其药理作用集中于心脑血管方向,其作用机制主要为抗氧化应激损伤、保护细胞线粒体功能等。本文通过分析总结其药理作用相关文献,以期为山楂叶总黄酮的药理及机制研究提供思路及参考。The flavonoids are the main active substance groups of Hawthorn leaves. Recent studies show that pharmacological researches are focused on the influence of heart and cerebral vessels. Main mechanisms involve anti-oxidative stress damage and protecting the function of mitochondria of cells etc. This paper reviews the relative pharmacology effect of Hawthorn leaves flavonoids to provide idea and reference for its pharmacological and mechanism research.

关 键 词：山楂叶 总黄酮 研究进展 

分 类 号：R285.5[医药卫生—中药学]