2例长期未确诊的足部疣状皮肤结核分析  

Long-term undiagnosed foot tuberculosis verrucosa cutis: 2 cases report

作　　者：马梦兰 黄永初 曹育春[1] MA Meng-lan;HUANG Yong-chu;CAO Yu-chun(Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 , Chin)

机构地区：[1]华中科技大学同济医学院附属同济医院,武汉430030

出　　处：《内科急危重症杂志》2018年第1期12-15,共4页Journal of Critical Care In Internal Medicine

基　　金：国家自然科学基金项目(No:81472000)

摘　　要：目的:总结2例长期未确诊的足部疣状皮肤结核患者未确诊的可能原因与诊断线索。方法:分析2例疣状皮肤结核患者的临床表现、组织病理特点及治疗经过,结合国内外相关文献进行总结。结果:2例患者病程分别长达30余年及10余年未确诊,根据临床表现中原发皮肤损害表现及组织病理发现肉芽肿性炎,结合病原学检查均诊断为疣状皮肤结核。经三联抗结核治疗1年后基本痊愈。结论:疣状皮肤结核的临床表现在发生、发展的过程中会有较大变化,但是重视病程中的基本皮肤损害及肉芽肿性炎的组织病理的相对稳定性的特点,再结合特异的病原学检查结果及诊断性治疗结果可以确诊。Objective： To summarize the probable cause and diagnosis of undiagnosed foot tuberculosis verrucosa cutis in 2 patients. Methods： The clinical manifestations,histopathological features and treatments of 2 patients with tuberculosis verrucosa cutis were analyzed,and the relevant literatures at home and abroad were summarized. Results： The foot tuberculosis verrucosa cutis with clinical course respectively for 30 years and more than 10 years in 2 cases was diagnosed in terms of primary skin lesions and the granulomatous inflammation in dermatopathology,in combination with etiology examination of tuberculosis. After a year of triad anti-tuberculosis treatment,the patients recovered well. Conclusion： The clinical manifestation of tuberculosis verrucosa cutis in the process of occurrence and development will have great changes,but the diagnosis is relatively easy to confirm if we capture the relatively stable characteristics of the primary skin lesions and the granulomatous inflammation in dermatopathology,combined with the specific etiology examination of tuberculosis and diagnostic treatment.

关 键 词：疣状皮肤结核 原发损害 肉芽肿性炎 

分 类 号：R529.4[医药卫生—内科学]