二芳甲基取代的大位阻酚的制备及其金属化研究  

Preparation and metallation of diarylmethyl-substituted bulky phenols

作　　者：罗晓军 祝飞凤 范国康 雷浩 LUO Xiao-jun;ZHU Fei-feng;FAN Guo-kang;LEI Hao(School of Chemistry and Materials Science ,Jinan University, Guangzhou 510632 ,P. R. C.)

机构地区：[1]暨南大学化学与材料学院,广东广州510632

出　　处：《西南民族大学学报（自然科学版）》2018年第2期157-163,共7页Journal of Southwest Minzu University(Natural Science Edition)

基　　金：国家自然科学基金青年项目(No.21301070);广州市"珠江科技新星"人才专项(No.201610010118);暨南大学科研培育与创新基金跃升计划项目(No.21615401)

摘　　要：以氯化锌和浓盐酸为催化剂,在加热和无溶剂的条件下,具不同取代基团的二芳甲醇与苯酚衍生物发生亲电取代反应,以较高产率合成了8种二芳甲基取代的大位阻酚化合物.利用合成的大位阻酚化合物在无水无氧条件下与正丁基锂反应又制备了8种相应的酚基锂化合物.所有目标产物的组成和结构都已通过核磁氢谱确证.上述化合物的制备为通过成盐复分解反应进一步制备含有低配位金属中心的酚基配合物奠定了基础.Under the catalysis by zinc chloride and concentrated hydrochloric acid, eight diarylmethyl-substituted bulky phenol compounds were prepared in high yields, through solvent-free eleetrophilie substitution reactions between various benzhydrol and phenol derivatives at high temperature. The corresponding lithium phenolate complexes were synthesized via deprotonation of the phenols with n-butyllithium under dry and aerobic condition. The compositions and structures of all target compounds were con- firmed by 1HNMR methods. These results would shed light on further preparation of low-coordinate metal phenolate complexes through salt metathesis.

关 键 词：二芳甲基 大位阻配体 酚基锂化合物 

分 类 号：O62[理学—有机化学]