异种(牛)脱细胞真皮基质联合耳甲腔成形术在开放性乳突根治术中的应用  

The application of cattle acelluar dermal matrix xenograft associate with conchoplasty in the open mastoidectomy

作　　者：曹琳[1] 朱富高[1] 李文娟 付涛[1] 张晓恒[1] 黄天桥[1] 纪彩丽 CAO Lin;ZHU Fugao;LI Wenjuan;FU Tao;ZHANG Xiaoheng;HUANG Tianqiao;JI Caili(Department of Otolaryngology Head and Neck Surgery, Affiliated Hospital of Medical College Qingdao University, Qingdao, 266003, Chin)

机构地区：[1]青岛大学医学院附属医院耳鼻咽喉头颈外科,山东青岛266003

出　　处：《临床耳鼻咽喉头颈外科杂志》2018年第7期507-510,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:探讨异种(牛)脱细胞真皮基质联合耳甲腔成形术在开放性乳突根治术中的临床应用及其意义。方法:133例慢性化脓性中耳炎患者行开放性乳突根治术+耳甲腔成形术,其中实验组70例患者采用异种(牛)脱细胞真皮基质覆于术腔表面,对照组63例未采用,对2组疗效进行相关分析比较。结果:实验组术后完全上皮化时间28.5d,干耳时间为27.15d,对照组术后完全上皮化时间60.75d,干耳时间为44.35d,2组比较差异均有统计学意义(P<0.01)。结论:异种(牛)脱细胞真皮基质联合耳甲腔成形术有利于开放性乳突根治术后术腔的恢复,减少术后感染及肉芽的发生,缩短上皮化时间,加快干耳。Objective：To study the value of acelluar dermal matrix xenografts associated with conchoplasty in the open mastoidectomy.Method：One hundred and thirty-three cases of chronic otitis media undergoing open mastoidectomy and conchoplasty were enrolled in this study.The effects were analyzed and compared between 70 cases in plastic group repaired by acelluar dermal matrix xenografts and 63 cases in control group.Result：The epithelization time is 28.5 dand the dry-ear time is 27.15 din plastic group.In control group,they were 60.75 dand 44.35 d respectively.The difference had statistical significance.Conclusion：The application of cattle acelluar dermal matrix xenograft associated with conchoplasty in the open mastoidectomy is beneficial to the recovery of the cavity which can shorten mastoid cavity epithelization time,promoting dry ear,reducing postoperative infection and granulation.

关 键 词：异种脱细胞真皮基质 耳甲腔成形术 乳突根治术 

分 类 号：R764.9[医药卫生—耳鼻咽喉科]