耳后注射甲强龙在中高频听力下降型突发性聋治疗中的疗效分析  

The effects of postauricular injection of methylprednisolone on medium-high frequency sudden hearing loss

作　　者：张天宇 尚小领[2] 谢亚学 林彦涛[2] 张青俊[2] 李栋[2] 辛运超 ZHANG Tianyu;SHANG Xiaoling;XIE gaxue;LIN gantao;ZHANG Qingjun;LI Dong;XIN Yunchao(Hebei North University, Zhangjiakou, 075000, China;Department of Otolaryngology, the First Affiliated Hospital of Hebei North University;Department of Otolaryngology, the Fourth Hospital of Hengshui)

机构地区：[1]河北北方学院,河北张家口075000 [2]河北北方学院附属第一医院耳鼻咽喉科 [3]衡水市第四人民医院耳鼻咽喉科

出　　处：《临床耳鼻咽喉头颈外科杂志》2018年第7期537-540,共4页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:研究耳后注射甲强龙作为补救方案在中高频听力下降型突发性聋治疗中的疗效。方法:筛选治疗2个疗程(14d)后无效的中高频听力下降型突发性聋患者45例,其中包括后续常规治疗25例及耳后注射甲强龙治疗20例,比较2组之间的疗效差异。结果:在250、500、1000、2000、4000、8000 Hz各频率,常规治疗组听力提高值依次为(6.30±5.00)dB HL,(3.80±5.52)dB HL,(5.35±5.50)dB HL,(15.60±11.84)dB HL,(19.60±13.46)dB HL,(15.40±12.90)dB HL,耳后注射组听力提高值依次为(5.35±6.22)dB HL,(2.50±3.00)dB HL,(4.65±6.60)dB HL,(23.75±10.75)dB HL,(25.75±11.73)dB HL,(30.50±14.50)dB HL。在2 000~8 000Hz常规治疗组和耳后注射组治疗有效率分别为44%和80%,差异有统计学意义(χ2=8.385,P<0.05)。结论:耳后注射甲强龙作为补救方案治疗中高频听力下降型突发性聋安全有效,可提高中高频听力下降型突发性聋患者的治疗有效率。Objective：To study the effects of postauricular injection of methylprednisolone on medium-high frequency sudden hearing loss.Method：The data of 45 patients with invalid treatment who were diagnosed as medium-high frequency sudden hearing loss were retrospectively studied.They were divided into postauricular injection group and non-postauricular injection group.The treatment efficiency and hearing improvement at each frequency were compared between the two groups.Result：The improvements of hearing threshold in the non-postauricular injection group were（6.30±5.00）dB HL,（3.80±5.52）dB HL,（5.35±5.50）dB HL,（15.60±11.84）dB HL,（19.60±13.46）dB HL,（15.40±12.90）dB HL at 250,500,1 000,2 000,4 000 and 8 000 Hz,respectively.The hearing improvements of the postauricular injection group were（5.35±6.22）dB HL,（2.50±3.00）dB HL,（4.65±6.60）dB HL,（23.75±10.75）dB HL,（25.75±11.73）dB HL,（30.50±14.50）dB HL at 250,500,1 000,2 000,4 000 and 8000 Hz,respectively.There were significant differences between the two groups in hearing improvements at 2 000-8 000 Hz.The treatment effective rates were 44% and 80%for the non-postauricular injection group and postauricular injection group respectively,which showed a significant difference（χ2=8.385,P〈0.05）.Conclusion：Postauricular injection of methylprednisolone as a remedy treatment is safe and effective for sudden hearing loss in middle and high frequency.

关 键 词：听觉丧失 突发性 耳后注射 甲强龙 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]